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Merck

11970

Sigma-Aldrich

1,3-Diphenyl-2-propenon

≥98.0% (GC)

Synonym(e):

Benzalacetophenon, Chalkon

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About This Item

Lineare Formel:
C6H5CH=CHCOC6H5
CAS-Nummer:
Molekulargewicht:
208.26
Beilstein:
1210466
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22

Assay

≥98.0% (GC)

Löslichkeit

dioxane: soluble 1 g/10 mL, clear, colorless

Funktionelle Gruppe

ketone
phenyl

SMILES String

O=C(\C=C\c1ccccc1)c2ccccc2

InChI

1S/C15H12O/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-12H/b12-11+

InChIKey

DQFBYFPFKXHELB-VAWYXSNFSA-N

Angaben zum Gen

rat ... Ar(24208)

Anwendung

1,3-Diphenyl-2-propenone was used in the preparation of pharmacologically-interesting heterocyclic systems like pyrazolines and pyrimidines[1].

Biochem./physiol. Wirkung

1,3-Diphenyl-2-propenone (chalcone) inhibits the proliferation of human breast cancer cell lines, MCF-7 and MDA-MB-231 by inducing apoptosis and blocking cell cycle progression in the G2/M phase[2]. It is an inhibitor of Plasmodium falciparum cyclin-dependent protein kinases[3].

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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