Direkt zum Inhalt
Merck

SIGMAR1

sigma non-opioid intracellular receptor 1

Synonyme:
ALS16, OPRS1, SIG-1R, SR-BP, SR-BP1, SRBP, hSigmaR1, sigma1R
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(10280) Summary: This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2008]
  • Mouse(18391) sigma non-opioid intracellular receptor 1
  • Rat(29336) sigma non-opioid intracellular receptor 1
  • domestic guinea pig(100135589) sigma non-opioid intracellular receptor 1
  • cow(538903) sigma non-opioid intracellular receptor 1
  • sheep(101116710) sigma non-opioid intracellular receptor 1
  • domestic cat(101084912) sigma non-opioid intracellular receptor 1
  • Zebrafish(393952) sigma non-opioid intracellular receptor 1
  • chicken(100859748) sigma non-opioid intracellular receptor 1
  • dog(481587) sigma non-opioid intracellular receptor 1
  • naked mole-rat(101707150) sigma non-opioid intracellular receptor 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Dextromethorphan -Lösung, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Dextromethorphan, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Dextromethorphan HBr, certified reference material, pharmaceutical secondary standard,
Spezies
human
Dextromethorphan -hydrobromid, meets USP testing specifications,
Spezies
human
Dextromethorphan -hydrobromid, European Pharmacopoeia (EP) Reference Standard,
Spezies
human

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
Pentazocine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Sigma-IR-Antikörper, Klon ICR-SIG1R-A, clone ICR-SIG1R-A, from rat,
Speziesreaktivität
human, mouse
Anwendung
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-SIGMAR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
ANTI-OPRS1 (CENTER) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, mouse
Anwendung
western blot
ANTI-OPRS1(N-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
flow cytometry
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Sigmar1,
Spezies
mouse