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PRKCB

protein kinase C, beta

Synonyme:
PKC-beta, PKCB, PRKCB1, PRKCB2
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(5579) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(18751) protein kinase C, beta
  • Rat(25023) protein kinase C, beta
  • Domestic Rabbit(100037719) protein kinase C, beta
  • sheep(101118410) protein kinase C, beta
  • naked mole-rat(101722702) protein kinase C, beta
  • domestic cat(101088970) protein kinase C, beta
  • chicken(416567) protein kinase C, beta
  • dog(489968) protein kinase C, beta
  • cow(282325) protein kinase C, beta

Custom & Knockdown Gene Products

Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Oleinsäure, ≥99% (GC),
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-PRKCB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
Anti-p-PKCβ (Ser660) Antibody, clone 2C11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
bovine, human, monkey, mouse, rabbit, rat
Anwendung
affinity binding assay
immunocytochemistry

inhibition assay

western blot
Anti-PKCβ Antibody, clone 2E13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, monkey, mouse
Anwendung
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-PRKCB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
Anti-Phospho-PKCalpha/beta II-T638/641 antibody produced in rabbit, ,
Speziesreaktivität
human
Anwendung
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Hispidin, solid, ≥98% (HPLC),
Spezies
human
H-7 -dihydrochlorid, ≥98% (HPLC),
Spezies
human
Tamoxifen -citrat (Salz), ≥99%,
Spezies
human
Oleinsäure, ≥99% (GC),
Spezies
human
UCN-01, ≥97% (HPLC), powder,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
Protein kinase CβII isozyme human, >85% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Prkcb,
Spezies
mouse
MISSION® esiRNA, targeting human PRKCB,
Spezies
human