PPARA
peroxisome proliferator-activated receptor alpha
Synonyme:
NR1C1, PPAR, PPARalpha, hPPAR
Spezies:
Human PPARA (5465), Mouse Ppara (19013), Rat Ppara (25747), domestic guinea pig Ppara (100135604), chicken PPARA (374120), naked mole-rat Ppara (101725514), Domestic Rabbit PPARA (100009308), Goat PPARA (100861393), sheep PPARA (100190976), dog PPARA (403654) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(5465) Summary: Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]
- Mouse(19013) peroxisome proliferator activated receptor alpha
- Rat(25747) peroxisome proliferator activated receptor alpha
- domestic guinea pig(100135604) peroxisome proliferator activated receptor alpha
- chicken(374120) peroxisome proliferator-activated receptor alpha
- naked mole-rat(101725514) peroxisome proliferator-activated receptor alpha
- Domestic Rabbit(100009308) peroxisome proliferator-activated receptor alpha
- Goat(100861393) peroxisome proliferator-activated receptor alpha
- sheep(100190976) peroxisome proliferator-activated receptor alpha
- dog(403654) peroxisome proliferator-activated receptor alpha
- Horse(100049840) peroxisome proliferator-activated receptor alpha
- domestic cat(101095837) peroxisome proliferator-activated receptor alpha
- domestic cat(100049013) peroxisome proliferator-activated receptor alpha
- cow(281992) peroxisome proliferator-activated receptor alpha
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Small Molecule - Activator
Small Molecule - Agonist
Produktnummer
Beschreibung
Spezies
Fenofibrat-verwandte Verbindung B, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Small Molecule - Antagonist
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-PPAR-α antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-PPAR α Antibody, ascites fluid, Chemicon®,
Speziesreaktivität
human, mouse
Anwendung
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-PPARα Antibody, clone 4G22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
bovine, canine, feline, human, monkey, mouse, porcine, rat
Anwendung
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-phospho PPAR alpha (Ser73), from rabbit,
Speziesreaktivität
bovine, human, mouse, rat
Anwendung
dot blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-PPARA antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, rat
Anwendung
western blot
Proteins
Produktnummer
Beschreibung
Spezies
PPARα, ligand binding domain (170-468) human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Spezies
human
PPARα isotype, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Spezies
human
PPARα isotype, ligand binding domain, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Spezies
human
esiRNA
Produktnummer
Beschreibung
Spezies