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Merck

P2RY12

purinergic receptor P2Y, G-protein coupled, 12

Synonyme:
ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12, SP1999
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(64805) Summary: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
  • Mouse(70839) purinergic receptor P2Y, G-protein coupled 12
  • Rat(64803) purinergic receptor P2Y, G-protein coupled, 12
  • dog(442958) purinergic receptor P2Y, G-protein coupled, 12
  • cow(408007) purinergic receptor P2Y, G-protein coupled, 12
  • sheep(101117897) purinergic receptor P2Y, G-protein coupled, 12
  • naked mole-rat(101701294) purinergic receptor P2Y, G-protein coupled, 12
  • domestic cat(101094044) purinergic receptor P2Y, G-protein coupled, 12
  • domestic guinea pig(100720551) purinergic receptor P2Y, G-protein coupled, 12

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Uridine 5′-(trihydrogen diphosphate) sodium salt from Saccharomyces cerevisiae, 95-100%,
Spezies
human

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
Ticagrelor, ≥98% (HPLC),
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Clopidogrelbisulfat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
(S)-(+)-Clopidogrel hydrogensulfate, ≥98% (HPLC),
Spezies
human
Prasugrel, ≥98% (HPLC),
Spezies
human
Clopidogrel-Bisulfat, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Ticlopidin -hydrochlorid, analytical standard, for drug analysis,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-P2RY12-Antikörper in Kaninchen hergestellte Antikörper, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-P2RY12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-P2RY12 Antibody, clone 2C12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
bovine, human
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-P2RY12 Antibody, clone 10B5.3.27, ,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-P2Y12 Receptor, from rabbit, purified by affinity chromatography,
Speziesreaktivität
human, rat
Anwendung
immunohistochemistry
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human P2RY12,
Spezies
human
MISSION® esiRNA, targeting mouse P2ry12,
Spezies
mouse