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HTR2A

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

Synonyme:
5-HT2A, HTR2
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3356) Summary: This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(15558) 5-hydroxytryptamine (serotonin) receptor 2A
  • Rat(29595) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • dog(403882) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • naked mole-rat(101708395) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • Horse(100009685) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • chicken(428070) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic guinea pig(100135545) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic cat(101081108) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • cow(407230) 5-hydroxytryptamine (serotonin) receptor 2A

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
(±)-DOI hydrochloride, ≥98% (HPLC), solid,
Spezies
human
Aripiprazole solution, 1.0 mg/mL (50:50 Methanol/Water with 1% 1N HCl), ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
α-Methylserotonin maleate salt, ≥98% (HPLC),
Spezies
human
Nortriptylin -hydrochlorid, ≥98% (HPLC), powder,
Spezies
human
Mianserin -hydrochlorid, ,
Spezies
human

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
DCEBIO, ≥98% (HPLC), solid,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
M100907, ≥98% (HPLC),
Spezies
human
Haloperidol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
2,2-Diphenylethylamin, 96%,
Spezies
rat
Haloperidol, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Haloperidol, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Serotonin receptor 2A/HTR2A Antibody, clone 9B11.1, clone 9B11.1, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-HTR2A, affinity isolated antibody,
Speziesreaktivität
human, rat
Anwendung
immunohistochemistry
western blot
Anti-HTR2A antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
western blot
Anti-5-HT-2A antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence

immunohistochemistry
Anti-Serotonin 2A (5-HT2A) Receptor (22-41) Rabbit pAb, liquid, Calbiochem®,
Speziesreaktivität
mouse, rat, sheep
Anwendung

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Mianserin -hydrochlorid, ,
Spezies
human
Trazodon -hydrochlorid, ≥99% (HPLC), powder,
Spezies
human
Pimozid, ,
Spezies
human, mouse, rat
Trimipramin -maleat (Salz), ≥98% (TLC), powder,
Spezies
human
Zimelidin -dihydrochlorid, solid,
Spezies
human

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Phenethylamin, 99%,
Spezies
rat, mouse, human
Phenethylamin, ≥99%,
Spezies
rat, mouse, human
Trazodone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Phenethylamin, purified by redistillation, ≥99.5%,
Spezies
rat, mouse, human
Trospiumhydrochlorid-Unreinheit Standard, British Pharmacopoeia (BP) Reference Standard,
Spezies
human

Small Molecule - Ligand

Produktnummer
Beschreibung
Spezies
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Spezies
human

Small Molecule - Metabolite

Produktnummer
Beschreibung
Spezies
5-Hydroxyindol-3-Essigsäure, ≥98% (HPLC), crystalline,
Spezies
human

Small Molecule - Mixed Agonist/Antagonist

Produktnummer
Beschreibung
Spezies
Mifepriston, ≥98%,
Spezies
human, mouse, rat
Haloperidol, powder,
Spezies
human, rat
Clozapin, ,
Spezies
human, rat

Small Molecule - Precursor

Produktnummer
Beschreibung
Spezies
5-Hydroxy-L-Tryptophan, powder,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Htr2a,
Spezies
mouse