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CDK7

cyclin-dependent kinase 7

Synonyme:
CAK1, CDKN7, HCAK, MO15, STK1, p39MO15
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(1022) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]
  • Mouse(12572) cyclin-dependent kinase 7
  • Rat(171150) cyclin-dependent kinase 7
  • domestic guinea pig(100725955) cyclin-dependent kinase 7
  • naked mole-rat(101702664) cyclin-dependent kinase 7
  • sheep(101119934) cyclin-dependent kinase 7
  • Horse(100049964) cyclin-dependent kinase 7
  • Zebrafish(405897) cyclin-dependent kinase 7
  • dog(608441) cyclin-dependent kinase 7
  • domestic cat(101086781) cyclin-dependent kinase 7
  • chicken(771294) cyclin-dependent kinase 7
  • cow(515462) cyclin-dependent kinase 7
  • fruit fly(31441) Cyclin-dependent kinase 7

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-Cdk7/CAK antibody produced in mouse, clone MO-1.1, ascites fluid,
Speziesreaktivität
human
Anwendung
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

microarray

western blot
Anti-CDK7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-CDK7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
western blot
Monoclonal Anti-CDK7 antibody produced in mouse, clone 1G5, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
Anti-phospho Cyclin-dependent kinase 7 (Thr170) Antibody, from rabbit, purified by affinity chromatography,
Speziesreaktivität
human, mouse, rat
Anwendung
ChIP
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Flavopiridol -hydrochlorid, ≥98% (HPLC), powder,
Spezies
human
Roscovitine, ≥98% (TLC),
Spezies
human, mouse, rat
Olomoucine, ≥98% (HPLC),
Spezies
human, rat

Proteins

Produktnummer
Beschreibung
Spezies
Cdk7/Cyclin H/MAT1 (CAK-Komplex)-Protein, aktiv, 10 µg, Active complex of recombinant full length human Cdk7, containing a C-terminal His6-tag, recombinant full-length human Cyclin H untagged & recombinant full-length human MAT1 containing an N-terminal GST-tag, for use in Kinase Assays.,
Spezies
human
CDK7/Cyclin H1/MNAT1, active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Cdk7,
Spezies
mouse
MISSION® esiRNA, targeting human CDK7,
Spezies
human

Small Molecule - Substrate

Produktnummer
Beschreibung
Spezies
Cdk7/9tide, ,
Spezies
human