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Key Documents

1494909

USP

Pantoprazole Related Compound A

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

Pantoprazole sulfone, 5-(Difluoromethoxy)-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]sulfone}-1H-benzimidazole

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About This Item

Formule empirique (notation de Hill):
C16H15F2N3O5S
Numéro CAS:
Poids moléculaire :
399.37
Numéro Beilstein :
9430498
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

pantoprazole

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

InChI

1S/C16H15F2N3O5S/c1-24-13-5-6-19-12(14(13)25-2)8-27(22,23)16-20-10-4-3-9(26-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21)

Clé InChI

FCJYMBZQIJDMMM-UHFFFAOYSA-N

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Application


  • Transcriptional profiling for drug repurposing in glioblastoma: This study utilized transcriptional profiling to identify therapeutic targets and repurpose drugs, including pantoprazole-related compounds, for treatment in glioblastoma. This approach underscores the utility of pantoprazole impurities in exploring new therapeutic avenues in pharmaceutical reference material research (Roddy et al., 2023).

  • Gastroprotective agent utilization: A drug utilization study in medicine and surgery wards highlighted the significant role of pantoprazole and its related compounds in managing gastrointestinal protection. This research emphasizes the importance of pantoprazole as a proton pump inhibitor and its impurities in ensuring the efficacy and safety of gastroprotective therapies (Koyani et al., 2023).

  • Synthesis and analysis of pantoprazole sodium sesquihydrate-related compound E: This study explored the synthesis and mechanism of formation of a specific pantoprazole-related compound, offering insights into the chemical stability and quality control of pantoprazole as a pharmaceutical ingredient. Such research is crucial for enhancing analytical methods in pharmaceutical research and ensuring drug safety and efficacy (Yari et al., 2019).

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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E Doyle et al.
Journal of chromatography, 527(1), 67-77 (1990-04-27)
This paper describes two fully automated assays. One for zaprinast, a cGMP specific phosphodiesterase inhibitor, which uses the Gilson-Advanced Automated Sample Processor combination, and the other for an H+/K+ ATPase inhibitor and its sulphone metabolite, which uses direct injection. Both
Dafang Zhong et al.
The Journal of pharmacy and pharmacology, 57(3), 341-349 (2005-04-06)
We have investigated the metabolism of pantoprazole and have provided an explanation for the formation mechanism of its metabolites. Metabolites found in the urine of rats after oral administration of pantoprazole sodium (25 mg kg(-1)) were analysed by liquid chromatography/ion

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