Y0002161

Nomegestrol acetate for ID and assay CRS

CRS, European Pharmacopoeia (EP) Reference Standard

• Synonyme(s) : Nomegestrol acetate, 17-Acetoxy-6-methyl-19-norpregna-4,6-diene-3,20-dione, NOMAc, Org 10486-0
• Formule empirique (notation de Hill): C₂₃H₃₀O₄
• Numéro CAS: 58652-20-3
• Poids moléculaire : 370.48
• Numéro MDL: MFCD00941390
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Famille d'API: megesterol
• Fabricant/nom de marque: EDQM
• Température de stockage: 2-8°C
• Chaîne SMILES: CC(=O)O[C@@]1(CC[C@H]2[C@@H]3C=C(C)C4=CC(=O)CC[C@@H]4[C@H]3CC[C@]12C)C(C)=O
• InChI: 1S/C23H30O4/c1-13-11-20-18(17-6-5-16(26)12-19(13)17)7-9-22(4)21(20)8-10-23(22,14(2)24)27-15(3)25/h11-12,17-18,20-21H,5-10H2,1-4H3/t17-,18-,20-,21+,22+,23+/m1/s1
• Clé InChI: IIVBFTNIGYRNQY-YQLZSBIMSA-N

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Nomegestrol acetate for ID and assay CRS EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Nomegestrol acetate (NOMAc) is a potent, highly selective progestogen, a full agonist at the progesterone receptor, with no or minimal binding to other steroid receptors. It shows potent antigonadotropic activity mediated at the hypothalamic and pituitary level with strong antiestrogenic effects and a partial antiandrogenic effect. NOMAc is used in various formulations as a contraceptive.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS08,GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H361fd,H400
• Conseils de prudence: P201 - P273 - P308 + P313
• Classification des risques: Aquatic Acute 1 - Repr. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable