SML1231

c-di-AMP sodium salt

≥98% (HPLC), powder, bacterial second messenger

• Synonyme(s) : 3′,5′-Cyclic diadenylic acid sodium salt, Adenylyl-(3′5′)-3′-adenylic acid, cyclic nucleotide sodium salt, Cyclic di-3′,5′-adenylate sodium salt, Cyclic diadenylate monophosphate sodium salt, Cyclic diadenylate sodium salt, Cyclic-di-AMP sodium salt
• Formule empirique (notation de Hill): C₂₀H₂₄N₁₀O₁₂P₂ · xNa⁺
• Numéro CAS: 54447-84-6
• Poids moléculaire : 658.41 (free acid basis)
• Code UNSPSC : 12352200
• ID de substance PubChem : 329825734
• Nomenclature NACRES : NA.77

Propriétés

• product name: c-di-AMP sodium salt, ≥98% (HPLC)
• Description: contains 1μmol of powder (approx. 0.7mg)
• Niveau de qualité: 100
• Pureté: ≥98% (HPLC)
• Forme: powder
• Couleur: white to beige
• Température de stockage: −20°C
• Chaîne SMILES: NC1=NC=NC2=C1N=CN2[C@H](O3)[C@H](O)[C@H](OP(OC[C@@H]4[C@@H](O5)[C@@H](O)[C@H](N6C=NC7=C6N=CN=C7N)O4)(O)=O)[C@H]3COP5(O)=O.C
• InChI: 1S/C20H24N10O12P2/c21-15-9-17(25-3-23-15)29(5-27-9)19-11(31)13-7(39-19)1-37-43(33,34)42-14-8(2-38-44(35,36)41-13)40-20(12(14)32)30-6-28-10-16(22)24-4-26-18(10)30/h3-8,11-14,19-20,31-32H,1-2H2,(H,33,34)(H,35,36)(H2,21,23,25)(H2,22,24,26)/t7-,8-,11-,12-,13-,14-,19-,20-/m1/s1
• Clé InChI: PDXMFTWFFKBFIN-XPWFQUROSA-N

Description

Actions biochimiques/physiologiques

It has a role in various signaling pathways. In Gram-positive bacteria, it influences cell growth and survival and modulates virulence. c-di-AMP is formed by diadenylate cyclases (DACs), which are cyclase domain-containing proteins.

c-di-AMP is a bacterial secondary messenger. c-di-AMP acts as a potent mucosal adjuvant stimulating both humoral and cellular responses.

Notes préparatoires

c-di-AMP is soluble in water (≥ 16 mM, limits have not been determined).

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable