N4256

Nicotinic acid adenine dinucleotide sodium salt

≥98%

• Synonyme(s) : Deamido NAD, Deamido NAD Sodium Salt, NAAD, NAAD Sodium Salt, Nicotinic Acid Adenine Dinucleotide Sodium Salt, Nicotinic Acid NAD Sodium Salt, Nicotinic acid NAD
• Formule empirique (notation de Hill) : C₂₁H₂₅N₆O₁₅P₂Na
• Numéro CAS: 104809-30-5
• Poids moléculaire : 686.39
• NACRES: NA.51
• PubChem Substance ID: 24897698
• UNSPSC Code: 41106305
• MDL number: MFCD00082430
• Form: powder
• Assay: ≥98%
• Solubility: H₂O: soluble-50 mg/mL, clear, colorless
• Biological source: synthetic (inorganic)

Propriétés

• biological source: synthetic (inorganic)
• Quality Segment: 200
• assay: ≥98%
• form: powder
• solubility: H₂O: soluble-50 mg/mL, clear, colorless
• storage temp.: −20°C
• SMILES string: [Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OCC4OC(C(O)C4O)[N]5=CC(=CC=C5)C(O)=O)C(O)C3O
• InChI: 1S/C21H27N6O15P2.Na.H/c22-17-12-18(24-7-23-17)27(8-25-12)20-16(31)14(29)11(41-20)6-39-44(36,37)42-43(34,35)38-5-10-13(28)15(30)19(40-10)26-3-1-2-9(4-26)21(32)33;;/h1-4,7-8,10-11,13-16,19-20,28-31H,5-6H2,(H,32,33)(H,34,35)(H,36,37)(H2,22,23,24);;
• InChI key: JSOFOHZYBCRUNK-UHFFFAOYSA-N

Description

General description

Nicotinic acid adenine dinucleotide (deamido-NAD, NAAD) is a closely related analog of NAD⁺. It is used to study the structure of nicotinate mononucleotide adenylyltransferase(s) (NMN/NaMN). NAAD is used as a substrate to study the specificity and kinetics of nicotinamide adenine dinucleotide synthetase(s) (NADS). In addition, it is also used as a co-substrate to study mechanisms of members of the Sir2 class of NAD⁺-dependent deacetylase.

Application

Nicotinic acid adenine dinucleotide sodium salt has been used as an internal standard during high performance liquid chromatography (HPLC) metabolite measurement. It has also been used as a substrate in nicotinamide adenine dinucleotide (NAD) biosynthesis.

Other Notes

Analog of β-NAD

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves