H3128

Calconcarboxylic acid

suitable for use as an indicator for the titration of calcium

• Synonyme(s) : 2-Hydroxy-1-(2-hydroxy-4-sulfo-1-naphthylazo)-3-naphthoic acid, 3-Hydroxy-4-(2-hydroxy-4-sulfo-1-naphthylazo)naphthalene-2-carboxylic acid, Patton and Reeder’s reagent
• Formule empirique (notation de Hill): C₂₁H₁₄N₂O₇S
• Numéro CAS: 3737-95-9
• Poids moléculaire : 438.41
• Numéro Beilstein : 727492
• Numéro CE : 223-117-0
• Numéro MDL: MFCD00004078
• Code UNSPSC : 12171500
• ID de substance PubChem : 24895550
• Nomenclature NACRES : NA.47

Propriétés

• Niveau de qualité: 100
• Forme: powder
• Pf: 300 °C
• Solubilité: 1 M NaOH: 10 mg/mL
• Application(s): diagnostic assay manufacturing; hematology; histology
• Température de stockage: room temp
• Chaîne SMILES: OC(=O)c1cc2ccccc2c(N=Nc3c(O)cc(c4ccccc34)S(O)(=O)=O)c1O
• InChI: 1S/C21H14N2O7S/c24-16-10-17(31(28,29)30)13-7-3-4-8-14(13)18(16)22-23-19-12-6-2-1-5-11(12)9-15(20(19)25)21(26)27/h1-10,24-25H,(H,26,27)(H,28,29,30)/b23-22-
• Clé InChI: MVQBFZXBLLMXGS-FCQUAONHSA-N

Description

Description générale

Calconcarboxylic acid is a useful indicator for calcium titrations with EDTA in the presence of magnesium. It is also required for the staining of proteins in gels.

Calconcarboxylic acid is also known as Patton-Reeder indicator and is used in the determination of calcium at pH 12. Calconcarboxylic acid is a chelating agent and is used in the preparation of chelating sorbent along with chemically modified silica LiChroprep-NH₂, for trace metal analysis. Calconcarboxylic acid coupled with 3-aminopropyltriethoxysilane (APS-CCA), a fluorescent probe, facilitates the medical detection of Ca²⁺ ions in the blood with minimal blood backgrounds using hydrophobic hexadecyltrimethoxysilane (HDS) as substrate in fluorimetric microarray method.

Application

Calconcarboxylic acid (CCA) has been used in the preparation of poly-CCA film for leukemia diagnosis by immobilization, hybridization of DNA and detection by methylene blue and differential pulse voltammetry.

Qualité

Contains an inert diluent.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves