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Key Documents

EXTRA2

Sigma-Aldrich

Mouse ExtrAvidin® Peroxidase Staining Kit antibody produced in goat

Synonyme(s) :

ExtrAvidin® Peroxidase Staining Kits

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.32

Type de produit anticorps

secondary antibodies

Utilisation

sufficient for 2,000 tests ELISA, Immunoblotting
sufficient for 200 tests Immunohistology

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Modification post-traductionnelle de la cible

unmodified

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Description générale

These kits comprise universal reagents for use with primary antibodies in immunohistology, ELISA, and immunoblotting.
ExtrAvidin® is a unique form of avidin, available only from Sigma, that combines the high specificity and affinity of avidin for biotin with low non-specific binding at physiological pH. ExtrAvidin® peroxidase exhibits high sensitivity with low background.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Caractéristiques et avantages

  • Use in immunohistology, ELISA, and immunoblotting assays.
  • Affinity Isolated Antibodies have been adsorbed with human IgG and IgM to minimize cross-reactivity.
  • Biotinylated antibodies contain a spacer which improves accessibility for the ExtrAvidin® conjugates.

Composants

• 3 mL ExtrAvidin®-Peroxidase
• 3 mL Biotinylated Secondary Antibodies
• Complete Instructions and Assay Protocols

Informations légales

ExtrAvidin is a registered trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Matheus L Medeiros et al.
Journal of inflammation research, 14, 6477-6489 (2021-12-10)
Methylglyoxal (MGO) is a highly reactive dicarbonyl species implicated in diabetic-associated diseases. Acute lung injury (ALI) symptoms and prognosis are worsened by diabetes and obesity. Here, we hypothesized that elevated MGO levels aggravate ALI, which can be prevented by metformin.
Akila L Oliveira et al.
Frontiers in physiology, 13, 860342-860342 (2022-04-15)
Methylglyoxal (MGO) is a highly reactive dicarbonyl compound implicated in diabetes-associated diseases. In vascular tissues, MGO induces the formation of advanced glycation end products (AGEs) that bounds its receptor RAGE, initiating the downstream tissue injury. Outside the cardiovascular system, MGO
Vladimirs Pilipenko et al.
Neuropharmacology, 144, 319-326 (2018-11-09)
Early manifestations of Alzheimer's disease (AD) include neuroinflammation, disrupted neurotransmission and cognitive deficits. Impairment of the GABAergic system is essentially involved in the pathogenesis of AD. Traditionally, agonists of GABAA receptors at doses above 1 mg/kg are known to possess memory

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