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Key Documents

933864

Sigma-Aldrich

Dimethyl isosorbide

greener alternative

BioRenewable, anhydrous, DMF and NMP substitute, ≥99%

Synonyme(s) :

Isosorbide dimethyl ether, 1,4:3,6-Dianhydrosorbitol 2,5-dimethyl ether, 1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol, 2,5-Di-O-methyl-1,4:3,6-dianhydro-D-glucitol, DMI

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About This Item

Formule empirique (notation de Hill):
C8H14O4
Numéro CAS:
Poids moléculaire :
174.19
Numéro Beilstein :
80854
Numéro MDL:
Code UNSPSC :
12352005
Nomenclature NACRES :
NA.21

Niveau de qualité

Pureté

≥99%

Forme

liquid

Caractéristiques du produit alternatif plus écologique

Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Couleur

colorless

Indice de réfraction

n20/D 1.461 (lit.)

Point d'ébullition

93-95 °C/0.1 mmHg (lit.)

Densité

1.15 g/mL at 25 °C (lit.)

Autre catégorie plus écologique

Chaîne SMILES 

CO[C@H]1COC2[C@@H](COC12)OC

InChI

1S/C8H14O4/c1-9-5-3-11-8-6(10-2)4-12-7(5)8/h5-8H,3-4H2,1-2H3/t5-,6+,7-,8-/m1/s1

Clé InChI

MEJYDZQQVZJMPP-ULAWRXDQSA-N

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Description générale

We are dedicated to providing Greener Alternative Products that adhere to The 12 Principles of Greener Chemistry. Dimethyl isosorbide (DMI) is a bio-based solvent that aligns with the principles of "Use of Renewable Feedstocks" and "Safer Solvents and Auxiliaries", making it a sustainable alternative to dipolar aprotic solvents like NMP and DMF. DMI′s high solubilization capacity makes it suitable to be used as a co-solvent for nonpolar drugs and in organic synthesis. Moreover, its exceptional properties, such as non-toxicity, non-irritation, and biodegradability, make it a safe and eco-friendly choice for both customers and the environment.

Application

  • Polymer membranes preparation
  • Peptide synthesis
  • Cross-coupling reactions
  • Co-solvent to improve solubility of nonpolar compounds
  • Lithium battery recycling

Caractéristiques et avantages

  • Bio-based
  • Made from Renewable Resource - straw
  • Non-toxic solvent
  • Non-irritation
  • Biodegradability
  • High solubility potential

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

240.8 °F - closed cup

Point d'éclair (°C)

116 °C - closed cup


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Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Dimethylisosorbide (DMI) as a Bio-Derived Solvent for Pd-Catalyzed Cross-Coupling Reactions
Wilson K L, et al.
Synlett, 29, 2293-2297 (2018)
A sustainable approach to cathode delamination using a green solvent
Onurcan Buken, Kayla Mancinia and Amrita Sarkar
Royal Society of Chemistry Advances, 11, 27356-27368 (2021)
Greening Fmoc/tBu solid-phase peptide synthesis
Musaimi O A, et al.
Green Chemistry, 4, 996-1018 (2020)
Nickel-Catalyzed Reductive Cross-Coupling of Aryl Bromides with Vinyl Acetate in Dimethyl Isosorbide as a Sustainable Solvent
Mincong S, et al.
Organic Letters, 24, 354?358-354?358 (2022)
Dimethyl Isosorbide As a Green Solvent for Sustainable Ultrafiltration and Microfiltration Membrane Preparation
Russo F, et al.
ACS sustainable chemistry & engineering, 8, 659?668-659?668 (2020)

Contenu apparenté

Why should you have to choose between solvents that are ecological and those that are reliable? Enjoy both at once with our biorenewable and greener solutions. Cyrene™ solvent is a new dipolar aprotic alternative to common REACH restricted solvents, such as N methyl-2-pyrrolidone (NMP) and Dimethylformamide (DMF).

Why should you have to choose between solvents that are ecological and those that are reliable? Enjoy both at once with our biorenewable and greener solutions. Cyrene™ solvent is a new dipolar aprotic alternative to common REACH restricted solvents, such as N methyl-2-pyrrolidone (NMP) and Dimethylformamide (DMF).

Why should you have to choose between solvents that are ecological and those that are reliable? Enjoy both at once with our biorenewable and greener solutions. Cyrene™ solvent is a new dipolar aprotic alternative to common REACH restricted solvents, such as N methyl-2-pyrrolidone (NMP) and Dimethylformamide (DMF).

Why should you have to choose between solvents that are ecological and those that are reliable? Enjoy both at once with our biorenewable and greener solutions. Cyrene™ solvent is a new dipolar aprotic alternative to common REACH restricted solvents, such as N methyl-2-pyrrolidone (NMP) and Dimethylformamide (DMF).

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