MABN738
Anti-OCT6 Antibody, clone KT110
clone KT110, from mouse
Synonyme(s) :
POU domain, class 3, transcription factor 1, Octamer-binding protein 6, Oct-6, Octamer-binding transcription factor 6, OTF-6, POU domain transcription factor SCIP
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Niveau de qualité
Forme d'anticorps
purified immunoglobulin
Type de produit anticorps
primary antibodies
Clone
KT110, monoclonal
Espèces réactives
mouse, human
Technique(s)
electrophoretic mobility shift assay: suitable
immunohistochemistry: suitable
western blot: suitable
Isotype
IgG1κ
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... SLC22A16(85413)
Description générale
Octamer-binding protein 6 (Oct-6) is also called POU domain, class 3, transcription factor 1 (Pou3f1), Octamer-binding transcription factor 6 (OTF-6) and POU domain transcription factor SCIP. Oct-6 is a transcription factor that specifically binds to the (5′-ATTTGCAT-3′) octamer motif. Oct-6 has been implicated in early embryogenesis, neurogenesis, keratinocyte differentiation and myelination in the peripheral nervous system.
Immunogène
Recombinant protein corresponding to mouse OCT6.
Application
Anti-OCT6 Antibody, clone KT110 is a highly specific mouse monoclonal antibody, that targets Oct-6 & has been tested in western blotting, IHC & Electrophoretic Mobility Shift Assay.
Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected OCT6 in mouse embryonic brain (D15.5) tissue.
Electophoretic Mobility Shift Assay (EMSA) Analysis: A representative lot detected SphK1 in nuclear extracts from RT4 Schwannoma or primay rat Shcwann cells (Prof. D. Meijer, Erasmus University Medical Center, Rotterdam.
Electophoretic Mobility Shift Assay (EMSA) Analysis: A representative lot detected SphK1 in nuclear extracts from RT4 Schwannoma or primay rat Shcwann cells (Prof. D. Meijer, Erasmus University Medical Center, Rotterdam.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Signaling
Developmental Signaling
Qualité
Evaluated by Western Blotting in H9 human embreyonic stem cell lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected OCT6 in 10 µg of H9 human embreyonic stem cell lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected OCT6 in 10 µg of H9 human embreyonic stem cell lysate.
Description de la cible
~50 kDa observed
Liaison
Replaces: MABN1060
Forme physique
Format: Purified
Protein A purified
Purified mouse monoclonal IgG1κ in buffer containing PBS and 0.9% sodium azide.
Stockage et stabilité
Stable for 1 year at 2-8°C from date of receipt.
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Vittoria Dickinson Bocchi et al.
Science (New York, N.Y.), 372(6542) (2021-05-08)
Deciphering how the human striatum develops is necessary for understanding the diseases that affect this region. To decode the transcriptional modules that regulate this structure during development, we compiled a catalog of 1116 long intergenic noncoding RNAs (lincRNAs) identified de
Michel Fries et al.
Cell reports, 42(8), 112985-112985 (2023-08-17)
The balance of contralateral and ipsilateral retinogeniculate projections is critical for binocular vision, but the transcriptional programs regulating this process remain ill defined. Here we show that the Pou class homeobox protein POU3F1 is expressed in nascent mouse contralateral retinal
Joshua Po Han Wu et al.
Frontiers in molecular neuroscience, 15, 921901-921901 (2022-08-09)
The cerebellar nuclear (CN) neurons are a molecularly heterogeneous population whose specification into the different cerebellar nuclei is defined by the expression of varying sets of transcription factors. Here, we present a novel molecular marker, Pou3f1, that delineates specific sets
Masaki Kinoshita et al.
Cell stem cell, 28(3), 453-471 (2020-12-04)
Pluripotent cells emerge as a naive founder population in the blastocyst, acquire capacity for germline and soma formation, and then undergo lineage priming. Mouse embryonic stem cells (ESCs) and epiblast-derived stem cells (EpiSCs) represent the initial naive and final primed
Sima Khazaei et al.
Cell, 186(6), 1162-1178 (2023-03-18)
Germline histone H3.3 amino acid substitutions, including H3.3G34R/V, cause severe neurodevelopmental syndromes. To understand how these mutations impact brain development, we generated H3.3G34R/V/W knock-in mice and identified strikingly distinct developmental defects for each mutation. H3.3G34R-mutants exhibited progressive microcephaly and neurodegeneration
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