ABD77

Anti-Dax1 Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Nuclear receptor subfamily 0 group B member 1, DSS-AHC critical region on the X chromosome protein 1, Nuclear receptor DAX-1, AHC
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: rat, human
• Technique(s): immunohistochemistry: suitable (paraffin); western blot: suitable
• Numéro d'accès NCBI: NP_000466
• Numéro d'accès UniProt: P51843
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... NR0B1(190)

Description

Description générale

Dax-1 is an orphan nuclear receptor and is required for the normal development of the hypothalamic-pituitary-adrenal-gonadal axis formation. Defects in Dax-1 are the cause of X-linked adrenal hypoplasia congenital (XL-AHC); also known as X-linked Addison disease (AHX). Dax-1 also has a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency by acting as a negative regulator of Oct3/4 in ES cells.

Spécificité

75% Homologogous to Mouse Dax1

Immunogène

KLH-conjugated linear peptide corresponding to the Region of Ligand binding of Human Dax1.

Application

Evaluated by Immunohistochemistry in Human and Rat adrenal gland tissue. Immunohistochemsitry Analysis: A 1:1000 dilution of this antibody detected Dax1 in Human and Rat glioblastoma adrenal gland tissue.

Research Category
Stem Cell Research

Research Sub Category
Pluripotent & Early Differentiation

This Dax1 antibody is validated for use in WB & IHC for the detection of the Dax1 protein.

Qualité

Evaluated by Western Blot in a Dax1 overexpressing HEK293 transfected cell line. Western Blot Analysis: A 1:2000 dilution of this antibody detected Dax1 in a Dax1 overexpressing HEK293 transfected cell line.

Description de la cible

~53 kDa observed

Liaison

Replaces: 04-445

Forme physique

Antigen Affinity Purified

Purified rabbit polyclonal serum in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
Dax1 overexpressing HEK293 transfected cell line

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable