AB15928
Anti-Vitamin K dependent protein S Antibody
from rabbit, purified by affinity chromatography
Synonyme(s) :
protein S (alpha), protein S, alpha, protein Sa, vitamin K-dependent plasma protein S
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Forme d'anticorps
affinity isolated antibody
Type de produit anticorps
primary antibodies
Clone
polyclonal
Produit purifié par
affinity chromatography
Espèces réactives
mouse, rat, rhesus macaque, monkey
Réactivité de l'espèce (prédite par homologie)
horse, chimpanzee, human
Technique(s)
western blot: suitable
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... PROS1(5627)
Description générale
Vitamin K dependent protein S is an anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
Spécificité
Monkey (93%) and Rat (93%) Rhesus Monkey (93%).
This antibody recognizes Vitamin K dependent protein S.
Immunogène
This antibody is generated from rabbits immunized with a KLH-conjugated linear peptide corresponding to residues surrounding the mature peptide region of Vitamin K dependent protein S.
Application
Detect Vitamin K dependent protein S using this Anti-Vitamin K dependent protein S Antibody validated for use in WB.
Immunoprecipitation Analysis: 1:50,000 dilution from a previous lot detected Vitamin K dependent protein S on 15 µg of normal mouse serum.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Apoptosis - Additional
Qualité
Evaluated by Western Blot in mouse liver tissue lysate.
Western Blot Analysis: : 1:1000 dilution of this antibody detected Vitamin K dependent protein S on 10 µg of mouse liver tissue lysate.
Western Blot Analysis: : 1:1000 dilution of this antibody detected Vitamin K dependent protein S on 10 µg of mouse liver tissue lysate.
Description de la cible
Approx. 69-75 kDa
Forme physique
Affinity purified
Purified rabbit polyclonal containing 0.1 M Tris-glycine, pH 7.4, 0.150 mM NaCl and 0.05% sodium azide.
Stockage et stabilité
Maintain refrigerated at 2-8°C for 1 year from date of receipt.
Remarque sur l'analyse
Control
Mouse liver tissue lysate
Mouse liver tissue lysate
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis.
Burstyn-Cohen, T; Heeb, MJ; Lemke, G
The Journal of Clinical Investigation null
Delphine Lumbroso et al.
Frontiers in immunology, 9, 358-358 (2018-03-17)
The complete resolution of inflammation requires the uptake of apoptotic polymorphonuclear cells (PMN) by local macrophages (efferocytosis) and the consequent reprogramming of the engulfing phagocytes to reparative and pro-resolving phenotypes. The tyrosine kinase receptors TYRO3, AXL, and MERTK (collectively named
Genetic dissection of TAM receptor-ligand interaction in retinal pigment epithelial cell phagocytosis.
Burstyn-Cohen, T; Lew, ED; Traves, PG; Burrola, PG; Hash, JC; Lemke, G
Neuron null
GAS6 is a key homeostatic immunological regulator of host-commensal interactions in the oral mucosa.
Maria Nassar et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(3), E337-E346 (2017-01-05)
The oral epithelium contributes to innate immunity and oral mucosal homeostasis, which is critical for preventing local inflammation and the associated adverse systemic conditions. Nevertheless, the mechanisms by which the oral epithelium maintains homeostasis are poorly understood. Here, we studied
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