575001

α-Synuclein, Human, Recombinant, E. coli

• Synonyme(s) : NACP
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.77

Propriétés

• Source biologique: human
• Niveau de qualité: 100
• Produit recombinant: expressed in E. coli
• Pureté: ≥95% (SDS-PAGE)
• Forme: liquid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; avoid repeated freeze/thaw cycles
• Adéquation: suitable for molecular biology
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Informations sur le gène: human ... SNCA(6622)

Description

Description générale

Research area: Neuroscience

Recombinant, human α-synuclein expressed in E. coli. α-Synuclein is an acidic neuronal protein of 140 amino acids (amino acid residues 1 -140).

Application

α-Synuclein, Human, Recombinant, E. coli has been used to enhance the filter trap assay for identification of aggregated alpha-synuclein in brain samples.

Actions biochimiques/physiologiques

α-Synuclein been implicated in the pathogenesis of Parkinson’s disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells.

Conditionnement

Please refer to vial label for lot-specific concentration.

Avertissement

Toxicity: Standard Handling (A)

Forme physique

In 100 mM NaCl, 20 mM Tris-HCl, 1 mM MgCl₂, pH 7.5.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Autres remarques

Kahle, P.J, et al. 2001. Am. J. Pathol.159, 2215.
Kim, J. 1997. Mol. Cells7, 78.
Paik, S.R. 1997. Arch. Biochem. Biophys.344, 325.
Jakes, R., et al. 1994. FEBS Lett.345, 27.
Ueda, K., et al. 1993. Proc. Natl. Acad. Sci. USA90, 11282.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable