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Merck
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Key Documents

07-585

Sigma-Aldrich

Anti-dimethyl-Histone H3 (Arg2) Antibody

serum, Upstate®

Synonyme(s) :

H3R2me2, Histone H3 (di methyl R2)

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

serum

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

human, chicken

Fabricant/nom de marque

Upstate®

Technique(s)

inhibition assay: suitable (peptide)
western blot: suitable

Isotype

IgG

Numéro d'accès NCBI

NM_003493

Numéro d'accès UniProt

Q16695

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

dimethylation (Arg2)

Informations sur le gène

human ... H3F3B(3021)

Spécificité

Broad species cross-reactivity expected
dimethyl-arginine at residue 2 of histone H3

Immunogène

peptide containing the sequence AdimRT, corresponding to dimethyl-arginine 2 of human histone H3

Application

Anti-dimethyl-Histone H3 (Arg2) Antibody is a Rabbit Polyclonal Antibody for detection of dimethyl-Histone H3 (Arg2) also known as H3R2me2, Histone H3 (di methyl R2) & has been validated in WB, PIA.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones

Qualité

routinely evaluated by immunoblot on acid-extracted proteins from chicken erythrocyte cells (Catalog # 13-107)

Description de la cible

Mr 17kDa

Forme physique

Serum
rabbit antiserum containing 0.05% sodium azide, before the addition of glycerol to 30%

Stockage et stabilité

2 years at -20°C

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Haolin Liu et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(37), E7717-E7726 (2017-08-30)
Two of the unsolved, important questions about epigenetics are: do histone arginine demethylases exist, and is the removal of histone tails by proteolysis a major epigenetic modification process? Here, we report that two orphan Jumonji C domain (JmjC)-containing proteins, JMJD5
Claudia Stein et al.
Nucleic acids research, 40(19), 9522-9533 (2012-08-21)
The protein arginine methyltransferase 6 (PRMT6) is a coregulator of gene expression and executes its repressing as well as activating function by asymmetric dimethylation of histone H3 at R2 (H3 R2me2a). Given that elevated expression levels of PRMT6 have been
Jihee Hong et al.
Journal of ginseng research, 46(3), 481-488 (2022-05-24)
Although the tumor-suppressive effects of ginsenosides in cell cycle have been well established, their pharmacological properties in mitosis have not been clarified yet. The chromosomal instability resulting from dysregulated mitotic processes is usually increased in cancer. In this study, we
PELP1 oncogenic functions involve alternative splicing via PRMT6.
Mann, M; Zou, Y; Chen, Y; Brann, D; Vadlamudi, R
Molecular Oncology null
Markus A Kleinschmidt et al.
PloS one, 7(8), e41446-e41446 (2012-08-24)
PRMT6 belongs to the family of Protein Arginine Methyltransferase (PRMT) enzymes that catalyze the methylation of guanidino nitrogens of arginine residues. PRMT6 has been shown to modify the tail of histone H3, but the in vivo function of PRMT6 is
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