850345P

14:0 PC (DMPC)

1,2-dimyristoyl-sn-glycero-3-phosphocholine, powder

• Synonyme(s) : 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine; DMPC; PC(14:0/14:0)
• Formule empirique (notation de Hill): C₃₆H₇₂NO₈P
• Numéro CAS: 18194-24-6
• Poids moléculaire : 677.93
• Code UNSPSC : 51191904
• Nomenclature NACRES : NA.25

Propriétés

• Pureté: >99% (TLC)
• Forme: powder
• Conditionnement: pkg of 1 × 1 g (850345P-1g); pkg of 1 × 200 mg (850345P-200mg); pkg of 1 × 25 mg (850345P-25mg); pkg of 1 × 500 mg (850345P-500mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand 850345P
• Type de lipide: phospholipids; cardiolipins
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O
• InChI: 1S/C36H72NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-35(38)42-32-34(33-44-46(40,41)43-31-30-37(3,4)5)45-36(39)29-27-25-23-21-19-17-15-13-11-9-7-2/h34H,6-33H2,1-5H3/t34-/m0/s1
• Clé InChI: CITHEXJVPOWHKC-UMSFTDKQSA-N

Description

Description générale

Dimyristoylphosphatidylcholine (DMPC) belongs to the phosphatidylcholine (PCs) family. It is composed of saturated and symmetric phospholipids with 14 carbon atoms. DMPC is zwitterionic glycerophospholipid and is associated with mammalian membranes.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

14:0 PC (DMPC) has been used:

• in the preparation of liposomes for dissipation monitoring and perforin binding and assembly by Quartz crystal microscopy studies.
• in anthraquinone liposomes generation for spectral studies
• in bicelles preparation along with phosphatidylinositol 4,5-bisphosphate for in vitro reconstitution of β2-adrenergic receptor

Actions biochimiques/physiologiques

Dimyristoylphosphatidylcholine (DMPC) in combination with cholesterol is used as biomembrane model. Oral supplementation of DMPC in apolipoprotein (apo) E−null mice, improves high density lipoprotein levels and other lipid profiles, preventing the pathogenesis of atherosclerosis.

Conditionnement

20 mL Clear Glass Screw Cap Vial (850345P-1g)

20 mL Clear Glass Screw Cap Vial (850345P-500mg)

5 mL Amber Glass Screw Cap Vial (850345P-200mg)

5 mL Amber Glass Screw Cap Vial (850345P-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable