L031180

Activator 42^®

0.25 M, configured for PerkinElmer, configured for Polygen, configured for MerMade

• Synonyme(s) : 5-[3,5-Bis(trifluoromethyl)phenyl]-1H-tetrazole Solution, 5-[3,5-Bis(trifluoromethyl)phenyl]-2H-tetrazole Solution, Activator 42^® Solution
• Numéro CAS: 175205-09-1
• Code UNSPSC : 41106305
• Nomenclature NACRES : NA.21

Propriétés

• Type: for DNA synthesis
• Gamme de produits: Proligo Reagents
• Conditions de stockage: dry at room temperature
• Concentration: 70-77 g/L (Activator 42 content, titration)
• Impuretés: ≤30 ppm water content (Karl Fischer)
• Couleur: clear
• Compatibilité: configured for MerMade; configured for PerkinElmer; configured for Polygen
• InChI: 1S/C9H4F6N4/c10-8(11,12)5-1-4(7-16-18-19-17-7)2-6(3-5)9(13,14)15/h1-3H,(H,16,17,18,19)
• Clé InChI: KKJFZIQEWZVVIV-UHFFFAOYSA-N

Description

Notes préparatoires

Acetronitrile / Activator 42 100 / 7 (v/w)

Autres remarques

Activator solution, containing 5-(3,5-bis(trifluoromethyl)phenyl)-1H-tetrazole (Activator 42) in acetonitrile, are mixed with solutions of phosphoramidites during the extension step.
The activator reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain.

Informations légales

This product and it use is are covered under US Patent Number 7,897,758

Activator 42 is a registered trademark of Sigma-Aldrich Co. LLC

Informations sur la sécurité

• Pictogrammes: GHS02,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H225,H302 + H312 + H332,H315,H319
• Conseils de prudence: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 41.0 °F
• Point d'éclair (°C): 5 °C