SAB4501488

Anti-GPR109 antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : G-protein coupled receptor 109B, G-protein coupled receptor HM74, G-protein coupled receptor HM74B, GPR109B, Nicotinic acid receptor 2
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 44 kDa
• Espèces réactives: rat, mouse, human
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:10000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• Numéro d'accès NCBI: P49019
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... HCAR3(8843)

Description

Description générale

Anti-GPR109 antibody detects endogenous levels of total GPR109 protein.

GPR109B (G-protein coupled receptor 109B) is also called as hydroxycarboxylic acid receptor 3 (HCA3) and HM74 (G-protein coupled receptor). It belongs to the subfamily of G-protein-coupled receptors (GPCR). GPR109B is expressed in adipose tissue, lung, spleen and peripheral blood leukocytes. It is mapped to human chromosome 12q24.31.

Immunogène

The antiserum was produced against synthesized peptide derived from human GPR109.

Immunogen Range: 285-334

Actions biochimiques/physiologiques

GPR109B (G-protein coupled receptor 109B) helps to carry out the activities of D-Phe and D-Trp on neutrophils. HCA3 receptors helps to activate ERK1/2 through PTX (Pertussis toxin)-sensitive Gi (inhibitory G) protein-dependent pathway.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable