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Key Documents

Y0000852

β-Estradiol 3-benzoate

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

1,3,5(10)-estratriène-3,17β-diol 3-benzoate, 3,17β-dihydroxy-1,3,5(10)-estratriène 3-benzoate

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About This Item

Formule empirique (notation de Hill):
C25H28O3
Numéro CAS:
Poids moléculaire :
376.49
Numéro Beilstein :
3107526
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

estradiol

Fabricant/nom de marque

EDQM

Pf

191-198 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

[H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(OC(=O)c5ccccc5)ccc24

InChI

1S/C25H28O3/c1-25-14-13-20-19-10-8-18(28-24(27)16-5-3-2-4-6-16)15-17(19)7-9-21(20)22(25)11-12-23(25)26/h2-6,8,10,15,20-23,26H,7,9,11-14H2,1H3/t20-,21-,22+,23+,25+/m1/s1

Clé InChI

UYIFTLBWAOGQBI-BZDYCCQFSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Used in a study of general steroid metabolism and clearing, as groundwork for anabolic steroid screening in athletes.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

Health hazard

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Carc. 2 - Repr. 1B

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3


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Lot/Batch Number

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Consulter la Bibliothèque de documents

María-Esther Cruz et al.
Alcoholism, clinical and experimental research, 38(6), 1611-1621 (2014-05-14)
Intragastric or intraperitoneal ethanol (EtOH) treatment inhibits reproductive functions in females and male rats. The area of the hypothalamus where these effects take place is unknown. As the participations of the preoptic-anterior hypothalamic area (POA-AHA) in regulating ovulation is asymmetric
Keiko Arakawa et al.
Neuroendocrinology, 100(2-3), 162-177 (2014-10-11)
Exposure to stressors such as foot shock (FS) leads to increased expression of multiple inflammatory factors, including the proinflammatory cytokine interleukin-1 (IL-1) in the brain. Studies have indicated that there are sex differences in stress reactivity, suggesting that the fluctuations
Camelia M Saffarini et al.
PloS one, 10(3), e0122290-e0122290 (2015-03-24)
Prostate cancer is the most frequent non-cutaneous malignancy in men. There is strong evidence in rodents that neonatal estrogen exposure plays a role in the development of this disease. However, there is little information regarding the effects of estrogen in
Jesús Olayo-Lortia et al.
The journal of sexual medicine, 11(10), 2428-2438 (2014-07-24)
The multiple partner choice arena (MPCA) is an experimental setup in which male rats display a significant shortening of ejaculation latency, which is the main characteristic of premature ejaculation (PE) in men. Thus, the MPCA is a potential animal model
Patricia J Allen et al.
Pharmacology, biochemistry, and behavior, 130, 22-33 (2015-01-07)
Creatine is an antioxidant, neuromodulator and key regulator of energy metabolism shown to improve depressive symptoms in humans and animals, especially in females. To better understand the pharmacological effects of creatine, we examined its influence on depression-related hippocampal gene expression

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