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Y0000046

β-Estradiol 17-valerate

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

1,3,5(10)-estratriène-3,17β-diol 17-pentanote

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About This Item

Formule empirique (notation de Hill):
C23H32O3
Numéro CAS:
979-32-8
Poids moléculaire :
356.50
Numéro Beilstein :
2480357
Numéro MDL:
MFCD00056541
Code UNSPSC :
41116107
ID de substance PubChem :
329830826
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

estradiol

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CCCCC(=O)OC1CCC2C3CCc4cc(O)ccc4C3CCC12C

InChI

1S/C23H32O3/c1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20,21)2/h7,9,14,18-21,24H,3-6,8,10-13H2,1-2H3

Clé InChI

RSEPBGGWRJCQGY-UHFFFAOYSA-N

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Estradiol valerate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

1250008

β-Estradiol, United States Pharmacopeia (USP) Reference Standard

Y0000314

Estradiol for peak identification, European Pharmacopoeia (EP) Reference Standard

E1620000

β-Estradiol hemihydrate, European Pharmacopoeia (EP) Reference Standard

E1600000

β-Estradiol 3-benzoate, European Pharmacopoeia (EP) Reference Standard

PHR1353

β-Estradiol, Pharmaceutical Secondary Standard; Certified Reference Material

Y0000852

β-Estradiol 3-benzoate, European Pharmacopoeia (EP) Reference Standard

1252003

Estradiol cypionate, United States Pharmacopeia (USP) Reference Standard

1251000

β-Estradiol 3-benzoate, United States Pharmacopeia (USP) Reference Standard

BP729

β-Estradiol hemihydrate, British Pharmacopoeia (BP) Assay Standard

1254009

β-Estradiol 17-valerate, United States Pharmacopeia (USP) Reference Standard

1250041

Estradiol Related Compound C, United States Pharmacopeia (USP) Reference Standard

1250020

Estradiol Related Compound B, United States Pharmacopeia (USP) Reference Standard

1252193

Estradiol cypionate System Suitability Mixture, United States Pharmacopeia (USP) Reference Standard

Y0001823

β-Estradiol 17-valerate, European Pharmacopoeia (EP) Reference Standard

BP396

β-Estradiol 3-benzoate, British Pharmacopoeia (BP) Reference Standard

1254031

Estradiol Valerate Identification Mixture, United States Pharmacopeia (USP) Reference Standard

PHR2228

β-Estradiol 3-methyl ether, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2227

α-Estradiol, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2839

Estradiol Cypionate, certified reference material, pharmaceutical secondary standard

PHR2858

β-Estradiol 3-benzoate, certified reference material, pharmaceutical secondary standard

PHR2859

Estradiol Related Compound C, pharmaceutical secondary standard, certified reference material

Pictogrammes

Health hazardEnvironment
GHS08,GHS09

Mention d'avertissement

Warning

Mentions de danger

H351,H361fd,H362,H410

Classification des risques

Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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Sigma-Aldrich

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C Egarter et al.
Acta obstetricia et gynecologica Scandinavica, 75(4), 386-393 (1996-04-01)
Two sequential hormone replacement regimens, containing either estradiol valerate plus medroxyprogesterone acetate (E2V/MPA) or conjugated estrogens plus medrogestone (CE/MED), were compared with respect to effects on climacteric symptoms, lipid metabolism, and hemostasis. In an open, multicenter study, 51 perimenopausal women
B von Schoultz
Climacteric : the journal of the International Menopause Society, 6 Suppl 2, 24-32 (2003-12-13)
A combination of 2 mg estradiol valerate with 2 mg dienogest (E2V/DNG) (Climodien, Schering AG, Berlin, Gemany) is the first continuous combined postmenopausal hormone replacement therapy (HRT) preparation to contain a progestogen with substantial antiandrogenic activity. A study of its
Sheridan M Hoy et al.
Drugs, 69(12), 1635-1646 (2009-08-15)
Estradiol valerate/dienogest is an oral contraceptive for women that combines the natural estrogen estradiol with the 19-nortestosterone derivative dienogest in a four-phasic formulation. Estradiol valerate/dienogest demonstrated contraceptive efficacy in a large (n = 1377), noncomparative, multicentre study in women aged
R M Machado-de-Sena et al.
Photodiagnosis and photodynamic therapy, 11(3), 275-282 (2014-05-06)
Vaginal candidiasis (VC) is a disease that affects thousands of women of childbearing age, mainly caused by Candida albicans fungus. Photodynamic therapy (PDT) uses photosensitizing substances that are nontoxic in the dark, but able to produce reactive oxygen species when
Franca Fruzzetti et al.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 28(5), 400-408 (2012-04-04)
Natural estrogens such as estradiol (E(2)) or its valerate ester (E(2)V) offer an alternative to ethinyl estradiol (EE). E(2)-containing combined oral contraceptives (COCs) have demonstrated sufficient ovulation inhibition and acceptable contraceptive efficacy. However, earlier formulations were generally associated with unacceptable
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