1.00574

NMP

for Peptide Synthesis

• Synonyme(s) : 1-Methyl-2-pyrrolidone, NMP, N-Methyl-2-pyrrolidone
• Formule empirique (notation de Hill): C₅H₉NO
• Numéro CAS: 872-50-4
• Poids moléculaire : 99.13
• Numéro MDL: MFCD00003193
• Code UNSPSC : 12352115
• Numéro de classement CE : 212-828-1
• Nomenclature NACRES : NA.22

Propriétés

• product name: 1-Methyl-2-pyrrolidone, for Peptide Synthesis
• Pression de vapeur: 0.32 hPa ( 20 °C)
• Niveau de qualité: 200
• Pureté: ≥99.7% (GC)
• Forme: liquid
• Température d'inflammation spontanée: 245 °C
• Puissance: 3598 mg/kg LD₅₀, oral (Rat); 8000 mg/kg LD₅₀, skin (Rabbit)
• Limite d'explosivité: 1.3-9.5 % (v/v)
• pH: 8.5-10.0 (20 °C, 100 g/L in H₂O)
• Point d'ébullition: 202 °C/1013 hPa
• Pf: -24 °C
• Température de transition: flash point 91 °C
• Densité: 1.03 g/cm³ at 20 °C
• Application(s): peptide synthesis
• Température de stockage: 2-30°C
• InChI: 1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
• Clé InChI: SECXISVLQFMRJM-UHFFFAOYSA-N

Description

Description générale

N-methyl-2-pyrrolidone (NMP) is an organic solvent that finds applications in numerous industries, including petrochemicals, plastics, microelectronics, and to produce pigments, cosmetics, and drugs. It is commonly used worldwide as an organic solvent, intermediate, or surfactant in various industrial and consumer applications. The unique characteristics of NMP, including its ability to mix with water and organic solvents, and its temperature, polarity, and composition stability, make it a solvent of great interest in extractive distillation.

Application

1-Methyl-2-pyrrolidone can be used as a solvent during the peptide bond formation reactions.

Informations sur la sécurité

• Pictogrammes: GHS07,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H315 - H319 - H335 - H360D
• Conseils de prudence: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Classification des risques: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 195.8 °F - Pensky-Martens closed cup
• Point d'éclair (°C): 91 °C - Pensky-Martens closed cup