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134708

Sigma-Aldrich

2-Bromo-2-nitro-1,3-propanediol

98%

Synonyme(s) :

BNPD, BNPK, Bronopol

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About This Item

Formule linéaire :
HOCH2C(Br)(NO2)CH2OH
Numéro CAS:
52-51-7
Poids moléculaire :
199.99
Numéro Beilstein :
1705868
Numéro CE :
200-143-0
Numéro MDL:
MFCD00007390
Code UNSPSC :
12352100
ID de substance PubChem :
24848173
Nomenclature NACRES :
NA.22

Pureté

98%

Forme

crystals

Pf

130-133 °C (lit.)

Solubilité

H2O: soluble 100 mg/mL, clear, colorless to faintly yellow

Chaîne SMILES 

OCC(Br)(CO)[N+]([O-])=O

InChI

1S/C3H6BrNO4/c4-3(1-6,2-7)5(8)9/h6-7H,1-2H2

Clé InChI

LVDKZNITIUWNER-UHFFFAOYSA-N

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Application

  • Effect of leave-on cosmetic antimicrobial preservatives on healthy skin resident Staphylococcus epidermidis.: This study examines the impact of various antimicrobial preservatives, including 2-Bromo-2-nitro-1,3-propanediol, on the microbiota of healthy skin, particularly focusing on Staphylococcus epidermidis. The findings suggest that such preservatives can influence the skin′s microbial balance, which is essential for maintaining skin health (Zhang et al., 2023).
  • Assessing the residual antibacterial activity of clinical materials disinfected with glutaraldehyde, o-phthalaldehyde, hydrogen peroxide or 2-bromo-2-nitro-1,3-propanediol by means of a bacterial toxicity assay.: This research assesses the residual antibacterial effects of various disinfectants, including 2-Bromo-2-nitro-1,3-propanediol, on clinical materials, contributing to improved disinfection protocols in healthcare settings (Lerones et al., 2004).
  • Development and testing of a microbiological assay to detect residual effects of disinfectant on hard surfaces.: This study developed a microbiological assay to evaluate the residual effects of disinfectants, including 2-Bromo-2-nitro-1,3-propanediol, on hard surfaces, aiming to enhance surface disinfection strategies in various industries (Mariscal et al., 1999).

Clause de non-responsabilité

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Pictogrammes

CorrosionExclamation markEnvironment
GHS05,GHS07,GHS09

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

4.1B - Flammable solid hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

2-Bromo-2-nitro-1, 3-propanediol (Bronopol) and its derivatives: Synthesis, properties, and application (a review).
Legin, G. Ya.
Pharmaceutical Chemistry Journal, 30(4), 273-284 (1996)
Ahmad Asadinezhad et al.
Colloids and surfaces. B, Biointerfaces, 77(2), 246-256 (2010-03-02)
Medical-grade polyvinyl chloride was surface modified by a multistep physicochemical approach to improve bacterial adhesion prevention properties. This was fulfilled via surface activation by diffuse coplanar surface barrier discharge plasma followed by radical graft copolymerization of acrylic acid through surface-initiated
Heisuke Oono et al.
Biocontrol science, 12(2), 55-57 (2007-07-17)
We evaluated bronopol as a practical alternative anti-fungal agent to malachite green for use in hatcheries. Repeated exposure everyday, just after fertilization to the stage of eggs showing eye development to 50 mg/L and 100 mg/L bronopol for 30 min
Andrew P Shinn et al.
Veterinary parasitology, 186(3-4), 229-236 (2011-12-14)
Pyceze™ (Novartis Animal Vaccines Ltd.) is licensed as a veterinary medicine to treat fungal infections in salmon, trout and their eggs. The active ingredient is bronopol, which due to its broad-spectrum activity has the potential to be an effective treatment
M Matczuk et al.
International journal of cosmetic science, 34(5), 451-457 (2012-05-23)
Bronopol (2-bromo-2-nitropropane-1,3-diol) is used as preservative in cosmetic industry. Its main role in commercial products consists in protection of the cosmetic composition stability by inhibiting the development of micro-organisms. Unfortunately, preservatives can also undergo the degradation processes. The aim of
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