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Discovery® C18 (5 µm) HPLC Columns

L × I.D. 10 cm × 4.6 mm, HPLC Column

Synonyme(s) :

Discovery RP18 HPLC Column

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About This Item

Code UNSPSC :
41115700
eCl@ss :
32110501
Nomenclature NACRES :
SB.52

product name

Colonne HPLC Discovery® C18, 5 μm particle size, L × I.D. 10 cm × 4.6 mm

Matériaux

stainless steel column

Agence

suitable for USP L1

Gamme de produits

Discovery®

Caractéristiques

endcapped

Fabricant/nom de marque

Discovery®

Conditionnement

1 ea of

Ampleur du marquage

12% Carbon loading

Paramètres

≤70 °C temp. range
400 bar pressure (5801 psi)

Technique(s)

HPLC: suitable
LC/MS: suitable

L × D.I.

10 cm × 4.6 mm

Superficie

300 m2/g

Couverture de surface

3 μmol/m2

Impuretés

<10 ppm metals

Matrice

silica gel, high purity, spherical particle platform
fully porous particle

Groupe de la matrice active

C18 (octadecyl) phase

Taille des particules

5 μm

Dimension de pores

180 Å

operating pH range

2-8

Application(s)

food and beverages

Technique de séparation

reversed phase

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Description générale

Utilisez les colonnes Discovery® C18 pour toutes les méthodes qui demandent une colonne C18. La forme exceptionnelle des pics, la reproductibilité et la stabilité en font la colonne de choix pour toutes les méthodes C18, des applications de routines à celles les plus exigeantes.

Application


  • Development of an HPLC-based guanosine monophosphate kinase assay and application to Plasmodium vivax guanylate kinase.: Utilizes the Discovery® C18 HPLC Column for developing a novel enzymatic assay, aiding in malaria research and potential therapeutic target exploration (Pedro et al., 2019).

Caractéristiques et avantages

  • Reproductibilité excellente
  • Forme exceptionnelle des pics des analytes basiques et acides
  • Séparations LC-MS stables à faible diffusion
  • Séparation des peptides et petites protéines
  • Hydrophobicité moindre que celle de nombreuses colonnes comparables, produisant une analyse plus rapide

Produits recommandés

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Informations légales

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificats d'analyse (COA)

Lot/Batch Number
283930-06
283930-05
283930-04
283930-03
283930-02

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

T R Shantha Kumar et al.
Journal of pharmaceutical and biomedical analysis, 38(1), 173-179 (2005-05-24)
A simple, precise and accurate isocratic reverse-phase liquid chromatography method with programmed wavelength detection has been validated to quantify DRF-4367 and Phenol red, simultaneously for application in rat in situ single pass intestinal perfusion study to assess intestinal permeability of
Abbas Khan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(24), 2423-2429 (2011-07-26)
A novel isocratic reversed-phase high performance liquid-chromatography/ultraviolet detection method for simultaneous determination of cefdinir and cefixime in human plasma was developed and validated after optimization of various chromatographic conditions and other experimental parameters. Sample preparation based on a simple extraction
Himal Paudel Chhetri et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 22(5), 483-487 (2014-12-05)
This study presents the optimization of a simple HPLC-UV method for the determination of metformin in human plasma. Ion pair separation followed by UV detection was performed on deproteinized human plasma samples. The separation was carried out on a Discovery
Ramisetti Nageswara Rao et al.
Journal of separation science, 32(9), 1312-1322 (2009-04-29)
Modafinil, adrafinil and their related substances were synthesized and analyzed by RP-LC with ESI-MS/MS. The ionization mode, polarity, cone voltage, and chromatographic conditions were evaluated. The optimum LC-MS conditions to obtain fragment ions indispensable for identification of the structures were
Sheelendra Pratap Singh et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(27), 2845-2851 (2011-09-06)
Tamoxifen is the agent of choice for the treatment of estrogen receptor-positive breast cancer. Tamoxifen is a substrate of P-glycoprotein (P-gp) and microsomal cytochrome P450 (CYP) 3A, and biochanin A (BCA) is an inhibitor of P-gp and CYP3A. Hence, it
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