SML1526

Eltoprazine hydrochloride

≥98% (HPLC)

• Synonyme(s) : 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-piperazine hydrochloride
• Formule empirique (notation de Hill): C₁₂H₁₆N₂O₂ · HCl
• Numéro CAS: 98206-09-8
• Poids moléculaire : 256.73
• Numéro MDL: MFCD06245586
• Code UNSPSC : 12352202
• ID de substance PubChem : 329825943
• Nomenclature NACRES : NA.77

Propriétés

• Pureté: ≥98% (HPLC)
• Forme: powder
• Couleur: white to beige
• Solubilité: H₂O: 10 mg/mL, clear
• Température de stockage: room temp
• Chaîne SMILES: [H]Cl.C1(OCCO2)=C2C(N3CCNCC3)=CC=C1
• InChI: 1S/C12H16N2O2.ClH/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12;/h1-3,13H,4-9H2;1H
• Clé InChI: JFSOSUNPIXJCIX-UHFFFAOYSA-N

Description

Description générale

Eltoprazine, a serotonergic agent, possesses specific anti-aggressive (serenic) properties in various animal models without triggering sedation, motor disturbances, or muscle relaxation.

Actions biochimiques/physiologiques

Eltoprazine hyrochloride is a serotonin 5-HT1A/1B receptor agonist that has been shown to reduce L-DOPA-induced dyskinesias in in experimental models of Parkinson′s Disease and in human patients. It has Ki values for 5-HT1A, 5-HT1B and 5-HT1C receptors of 40 nM and 52 nM, respectively.

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H301,H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable