Accéder au contenu
MilliporeSigma
Toutes les photos(2)

Principaux documents

P8087

Sigma-Aldrich

Monoclonal Anti-Plakoglobin (Catenin γ) antibody produced in mouse

clone 15F11, ascites fluid, buffered aqueous solution

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme

Sélectionner une taille de conditionnement

100 μL
701,00 $
0.2 ML
744,00 $

701,00 $


Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit.

Devis pour commande en gros

Sélectionner une taille de conditionnement

Changer de vue
100 μL
701,00 $
0.2 ML
744,00 $

About This Item

Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

701,00 $


Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit.

Devis pour commande en gros

Source biologique

mouse

Niveau de qualité

Conjugué

unconjugated

Forme d'anticorps

ascites fluid

Type de produit anticorps

primary antibodies

Clone

15F11, monoclonal

Forme

buffered aqueous solution

Poids mol.

antigen 85 kDa

Contient

15 mM sodium azide

Espèces réactives

bovine, canine, human

Technique(s)

immunocytochemistry: suitable using cultured cells
immunohistochemistry (frozen sections): suitable
immunoprecipitation (IP): suitable
indirect immunofluorescence: 1:1,000 using cultured MDBK cells
microarray: suitable
western blot: 1:2,000 using cultured MDBK cells

Isotype

IgG1

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... JUP(3728)

Description générale

Plakoglobin is a desmosomal protein that regulates developmental signalling in vertebrates. Tyrosine phosphorylation of plakoglobin has been linked to adenocarcinomas . Plakoglobin may function as a tumor suppressor in ovarian and breast cancers .

Spécificité

The antibody recognizes the plakoglobin (catenin-γ) molecule (85 kDa and possibly a slightly lower band) by immunoblotting. It does not cross-react with β-catenin. The antibody reacts with plakoglobin in bovines, humans and dogs, but does not react with β catenin.

Immunogène

recombinant chicken plakoglobin.

Application

Monoclonal anti-plakoglobin (catenin γ) antibody is suitable for use in immunocytochemistry (using MDCK cells), immunoprecipitation, and in immunoblotting . The antibody may also be used for immunohistochemistry (frozen sections), microarray, western blot (1:500, using cultured MDBK cells) and indirect immunofluorescence (1:1000, using cultured MDBK cells).

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Vous ne trouvez pas le bon produit ?  

Essayez notre Outil de sélection de produits.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number

Vous ne trouvez pas la bonne version ?

Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

S Shibamoto et al.
Cell adhesion and communication, 1(4), 295-305 (1994-01-01)
The effect of hepatocyte growth factor/scatter factor (HGF/SF) and epidermal growth factor (EGF) on cadherin-mediated adhesion of human carcinoma cells was studied. HGF/SF induced scattering of colonic adenocarcinoma HT29 and gastric adenocarcinomas MKN7 and MKN74 cells. Likewise, EGF induced scattering
Rene L Begay et al.
JACC. Clinical electrophysiology, 4(4), 504-514 (2018-08-02)
The purpose of this study was to assess the phenotype of Filamin C (FLNC) truncating variants in dilated cardiomyopathy (DCM) and understand the mechanism leading to an arrhythmogenic phenotype. Mutations in FLNC are known to lead to skeletal myopathies, which
H Aberle et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(14), 6384-6388 (1995-07-03)
The gene encoding human plakoglobin was mapped to chromosome 17q12-q22. An intragenic restriction fragment length polymorphism was used to localize the plakoglobin gene distal to locus KRT10 and proximal to the marker D17S858. The plakoglobin gene colocalizes with the polymorphic
Carlos Bueno-Beti et al.
Progress in pediatric cardiology, 64, None-None (2022-03-19)
The diagnosis of arrhythmogenic cardiomyopathy (ACM) is challenging especially in children at risk of adverse events. Analysis of cardiac myocyte junctional protein distribution may have diagnostic and prognostic implications, but its utility is limited by the need for a myocardial
Willem B van Ham et al.
Journal of cardiovascular development and disease, 10(8) (2023-08-25)
The development of the normal human heart, ranging from gestational age to the mature adult heart, relies on a very delicate and timely orchestrated order of processes. One of the most striking alterations in time is the gradual extinction of

Questions

Reviews

No rating value

Active Filters

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique