peptide CIELKSELGRKWHKASN corresponding to residues 172-188 of human P2Y14 extracellular loop.
Description de la cible
P2Y14 belongs to the P2Y receptor family that is part of the G-protein coupled receptor superfamily. P2Y14 is expressed in several tissues including brain, lung, and several cells of hematopoietic origin such as T lymphocytes and dendritic cells. This receptor is apparently involved in chemotaxis, maturation of immature dendritic cells, and neuroimmune regulation.
Forme physique
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide.
Reconstitution
Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%).
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Neurofibromatosis type 1 (NF1) is characterized by nerve tumors called neurofibromas, in which Schwann cells (SCs) show deregulated RAS signaling. NF1 is also implicated in regulation of cAMP. We identified the G-protein-coupled receptor (GPCR) P2ry14 in human neurofibromas, neurofibroma-derived SC
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