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M2172

Sigma-Aldrich

1-Thioglycérol

BioXtra, ≥97%

Synonyme(s) :

α-Monothioglycérol, α-Thioglycérol, 3-Mercapto-1,2-propanediol

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10 ML
154,00 $
50 ML
547,00 $
100 ML
913,00 $

154,00 $

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10 ML
154,00 $
50 ML
547,00 $
100 ML
913,00 $

About This Item

Formule linéaire :
HSCH2CH(OH)CH2OH
Numéro CAS:
96-27-5
Poids moléculaire :
108.16
Beilstein:
1732046
Numéro CE :
202-495-0
Numéro MDL:
MFCD00004879
Code UNSPSC :
12352211
ID de substance PubChem :
24896709
Nomenclature NACRES :
NA.25

154,00 $

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Devis pour commande en gros

Gamme de produits

BioXtra

Essai

≥97%

Forme

liquid

Impuretés

≤0.0005% Phosphorus (P)

Résidus de calcination

≤0.1%

Indice de réfraction

n20/D 1.527 (lit.)

pb

118 °C/5 mmHg (lit.)

Densité

1.25 g/mL at 25 °C (lit.)

Traces de cations

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.02%
Pb: ≤0.001%
Zn: ≤0.0005%

Température de stockage

2-8°C

Chaîne SMILES 

OCC(O)CS

InChI

1S/C3H8O2S/c4-1-3(5)2-6/h3-6H,1-2H2

Clé InChI

PJUIMOJAAPLTRJ-UHFFFAOYSA-N

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Catégories apparentées

Description générale

1-Thioglycerol stimulates the synthesis of porphyrin in aerobically growing Escherichia coli. It is an inhibitor of glycerol kinase activity in vitro and in situ. [1]

Application

It has been used in a study to assess thiol-sensitive genes and promoters of Escherichia coli. [2] [3]

Notes préparatoires

This product is miscible in ethanol (1 ml/ml, 50%, v/v), yielding a clear, colorless solution. It is also miscible in water (0.1 M).

Pictogrammes

Skull and crossbones
GHS06

Mention d'avertissement

Danger

Mentions de danger

H302,H311 + H331,H315,H317

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Skin Irrit. 2 - Skin Sens. 1B

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

210.2 °F - closed cup

Point d'éclair (°C)

99 °C - closed cup

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificats d'analyse (COA)

Lot/Batch Number
0000431413
0000431414
0000431414
0000431413
0000406286

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

G T Javor et al.
Journal of bacteriology, 170(7), 3291-3293 (1988-07-01)
Mu dX(lac) insertion mutants of Escherichia coli CSH50 in which the expression of the lacZ gene was sensitive to the presence of exogenous 1-thioglycerol or dithiothreitol were isolated. Both stimulatory and inhibitory mutants were found. The existence of several thiol-sensitive
W K Seltzer et al.
Life sciences, 39(16), 1417-1424 (1986-10-20)
The infantile form of glycerol kinase (GK) deficiency (McKusick No. 30703) (1) is characterized by adrenal cortical insufficiency, adrenal hypoplasia and developmental delay. The underlying biochemical mechanism(s) responsible for the observed clinical presentations are undetermined. Pursuant to our examination of
G T Javor
Journal of bacteriology, 171(10), 5607-5613 (1989-10-01)
The effect of 1-thioglycerol on the expression of genes of Escherichia coli was investigated. Pulse-labeled proteins from aerobically growing, 1-thioglycerol-treated E. coli were separated by two-dimensional gel electrophoresis, and their radioactivities were compared with those of identical proteins from nontreated
Nadja Franz et al.
Organic & biomolecular chemistry, 7(24), 5207-5218 (2009-12-22)
Hydrophilic/hydrophobic patterning is a powerful strategy to control folding in non-natural polymers/oligomers. In this contribution, we present a novel strategy for the preparation of alternating hydrophilic/hydrophobic patterned non-natural peptide foldamers. This strategy relies on the post-modification of a reactive peptide
S Kanagaraja et al.
Journal of biomedical materials research, 46(4), 582-591 (1999-07-09)
Monolayers of glutathione (GSH) and 3-mercapto-1,2-propanediol (MG) on gold were tested for their bioreactivity by assessing the degree of inflammatory reaction as manifested by the adherence and activation of platelets and white blood cells (wbc) after exposure to blood ex
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Questions

1–3 of 3 Questions  

  1. How does the storage temperature relate to shipping conditions?

    1 answer

    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

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  2. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  3. What is the concentration of the 1-thioglycerol?

    1 answer

    1. The liquid is not a solution of 1-thioglycerol in some solvent. Rather, it is a neat liquid (i.e., essentially pure 1-thioglycerol). Based on a density of 1.245 g/mL and a molecular weight of 108.2 g/mole, one can calculate an effective molarity of 11.5 M. This information may be found on the M1753 product information sheet.

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