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I8140

Sigma-Aldrich

IgG from rabbit serum

technical grade, ≥80% (SDS-PAGE), buffered aqueous solution

Synonyme(s) :

Rabbit IgG

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10 MG
47,90 $
50 MG
191,00 $

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10 MG
47,90 $
50 MG
191,00 $

About This Item

Numéro MDL:
MFCD00165673
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

47,90 $

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Conjugué

unconjugated

Niveau de qualité

200

Qualité

technical grade

Essai

≥80% (SDS-PAGE)

Forme

buffered aqueous solution

Conditions d'expédition

dry ice

Température de stockage

−20°C

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Application

IgG from rabbit serum has been used:
  • as a reference, standard or blocking agent in many immunoassays including dot blots, ELISA, Westerns, IEP, and immunodiffusion assays
  • in arthus reaction[1]
  • in chromatin immunoprecipitation[2]

Actions biochimiques/physiologiques

Immunoglobulin G (IgG) regulates the immune responses such as phagocytosis and is also involved in the development of autoimmune diseases.[3] IgG1 regulates complement fixation in mice.[4]

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.2, containing 15 mM sodium azide

Notes préparatoires

Rabbit IgG is purified via fractionation from pooled normal rabbit serum

Remarque sur l'analyse

Immunoelectrophoresis (IEP) is used to establish the identity of the Rabbit IgG. . A single major arc of precipitation in the gamma region is observed versus anti-rabbit whole serum and anti-rabbit IgG. Minor gamma arcs may be present versus anti-rabbit whole serum

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
0000393261
0000362912
0000320936
0000345835
0000320936

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Consulter la Bibliothèque de documents

Mhairi Laird et al.
Endocrinology, 158(4), 920-935 (2017-03-23)
Androgens are essential for the normal function of mature antral follicles but also have a role in the early stages of follicle development. Polycystic ovary syndrome (PCOS), the most common cause of anovulatory infertility, is characterized by androgen excess and
Elena Matveeva et al.
Cell discovery, 2, 15046-15046 (2016-07-28)
Specialized chromatin structures such as nucleosomes with specific histone modifications decorate exons in eukaryotic genomes, suggesting a functional connection between chromatin organization and the regulation of pre-mRNA splicing. Through profiling the functional location of Poly (ADP) ribose polymerase, we observed
Frances Rena Bahjat et al.
Arthritis and rheumatism, 58(5), 1433-1444 (2008-04-29)
To assess whether R788, an orally bioavailable small molecule inhibitor of spleen tyrosine kinase (Syk)-dependent signaling, could modulate disease in lupus-prone (NZB x NZW)F1 (NZB/NZW) mice via inhibition of Fc receptor (FcR) and B cell receptor signaling. R788 was administered
Aluya R Oseghale et al.
Blood cells, molecules & diseases, 79, 102345-102345 (2019-07-28)
Pharmacologic induction of fetal hemoglobin (HbF) is an effective strategy for treating sickle cell disease (SCD) by ameliorating disease severity. Hydroxyurea is the only FDA-approved agent that induces HbF, but significant non-responders and requirement for frequent monitoring of blood counts
Lily Chien Wang et al.
DNA repair, 7(12), 1973-1981 (2008-09-13)
Fanconi anemia (FA) is a recessive genetic disorder characterized by hypersensitivity to crosslinking agents that has been attributed to defects in DNA repair and/or replication. FANCD2 and the FA core complex bind to chromatin during DNA replication; however, the role
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Questions

1–2 of 2 Questions  

  1. Does this product contain azide? if so, what is the concentration?

    1 answer

    1. Yes, this product contains 15 mM sodium azide, as mentioned in the 'DESCRIPTION' section.

      Helpful?

  2. What is the concentration of this IgG?

    1 answer

    1. The protein concentration for I8410 is batch-dependent and ranges from 10.0 - 13.0 mg/mL.

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