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Y0000886

1-Methylpiperazine

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

1-Methylpiperazine

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About This Item

Formule empirique (notation de Hill):
C5H12N2
Numéro CAS:
109-01-3
Poids moléculaire :
100.16
Numéro Beilstein :
102724
Numéro MDL:
MFCD00005966
Code UNSPSC :
41116107
ID de substance PubChem :
329831205
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Densité de vapeur

3.5 (vs air)

Famille d'API

cyclizine

Fabricant/nom de marque

EDQM

Indice de réfraction

n20/D 1.466 (lit.)

Point d'ébullition

138 °C (lit.)

Densité

0.903 g/mL at 25 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CN1CCNCC1

InChI

1S/C5H12N2/c1-7-4-2-6-3-5-7/h6H,2-5H2,1H3

Clé InChI

PVOAHINGSUIXLS-UHFFFAOYSA-N

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cyclizine impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

C3090000

Cyclizine hydrochloride, (European Pharmacopoeia (EP) Reference Standard)

Y0000887

Cyclizine impurity B, European Pharmacopoeia (EP) Reference Standard

1154004

Cyclizine hydrochloride, United States Pharmacopeia (USP) Reference Standard

1154015

1-Methylpiperazine, United States Pharmacopeia (USP) Reference Standard

1424209

Methylbenzhydrol, United States Pharmacopeia (USP) Reference Standard

1051602

Benzhydrol, United States Pharmacopeia (USP) Reference Standard

BP096

Cyclizine hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR2071

Benzhydrol, Pharmaceutical Secondary Standard; Certified Reference Material

BP1118

1-Methylpiperazine, British Pharmacopoeia (BP) Reference Standard

Pictogrammes

FlameCorrosionExclamation mark
GHS02,GHS05,GHS07

Mention d'avertissement

Danger

Mentions de danger

H226,H314,H317,H332

Classification des risques

Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - Skin Sens. 1B

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

88.7 °F - closed cup

Point d'éclair (°C)

31.5 °C - closed cup

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Almeqdad Y Habashneh et al.
Archiv der Pharmazie, 347(6), 415-422 (2014-03-13)
A new series of N1-(flavon-6-yl)amidrazones were synthesized by reacting the hydrazonoyl chloride derived from 6-aminoflavone with the appropriate sec-cyclic amines. The antitumor activities of these compounds were evaluated on breast cancer (MCF-7) and leukemic (K562) cell lines. Among the compounds
Jin-Ping Li et al.
Drug design, development and therapy, 9, 1027-1062 (2015-03-04)
Danusertib (Danu) is a pan-inhibitor of Aurora kinases and a third-generation breakpoint cluster region-Abelson murine leukemia viral oncogene homolog 1 (Bcr-Abl) tyrosine kinase inhibitor, but its antitumor effect and underlying mechanisms in the treatment of human breast cancer remain elusive.
Son T Nguyen et al.
Bioorganic & medicinal chemistry, 23(9), 2024-2034 (2015-03-31)
Recently we described a novel pyranopyridine inhibitor (MBX2319) of RND-type efflux pumps of the Enterobacteriaceae. MBX2319 (3,3-dimethyl-5-cyano-8-morpholino-6-(phenethylthio)-3,4-dihydro-1H-pyrano[3,4-c]pyridine) is structurally distinct from other known Gram-negative efflux pump inhibitors (EPIs), such as 1-(1-naphthylmethyl)-piperazine (NMP), phenylalanylarginine-β-naphthylamide (PAβN), D13-9001, and the pyridopyrimidine derivatives. Here

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