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B0900000

Benzylpenicillin sodium

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Penicillin G sodium salt, Benzylpenicillin sodium salt

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About This Item

Formule empirique (notation de Hill):
C16H17N2NaO4S
Numéro CAS:
69-57-8
Poids moléculaire :
356.37
Numéro Beilstein :
3834217
Numéro MDL:
MFCD00069666
Code UNSPSC :
41116107
ID de substance PubChem :
329773133
Nomenclature NACRES :
NA.24

Famille d'API

penicillin & derivatives

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

[Na+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

InChI

1S/C16H18N2O4S.Na/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

Clé InChI

FCPVYOBCFFNJFS-LQDWTQKMSA-M

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Benzylpenicillin sodium EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.

Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

1504503

Penicilline V potassium salt, United States Pharmacopeia (USP) Reference Standard

1502508

Penicillin G potassium salt, United States Pharmacopeia (USP) Reference Standard

1502009

Penicillin G benzathine, United States Pharmacopeia (USP) Reference Standard

B0700000

Penicillin G potassium salt, European Pharmacopoeia (EP) Reference Standard

B0500000

Benzathine benzylpenicillin, European Pharmacopoeia (EP) Reference Standard

P3090000

Procaine benzylpenicillin, European Pharmacopoeia (EP) Reference Standard

P1100000

Penicilline V potassium salt, European Pharmacopoeia (EP) Reference Standard

P1000000

Phenoxymethylpenicillin, European Pharmacopoeia (EP) Reference Standard

1504489

Penicillin V, United States Pharmacopeia (USP) Reference Standard

1502552

Penicillin G procaine, United States Pharmacopeia (USP) Reference Standard

1502701

Penicillin G sodium, United States Pharmacopeia (USP) Reference Standard

BP282

Penicilline V potassium salt, British Pharmacopoeia (BP) Reference Standard

BP295

Procaine benzylpenicillin, British Pharmacopoeia (BP) Reference Standard

Y0002039

Benzathine phenoxymethylpenicillin for system suitability, European Pharmacopoeia (EP) Reference Standard

Y0002000

Benzathine benzylpenicillin for peak identification, European Pharmacopoeia (EP) Reference Standard

Y0002001

Benzathine phenoxymethylpenicillin, European Pharmacopoeia (EP) Reference Standard

Y0002077

Procaine benzylpenicillin for peak identification, European Pharmacopoeia (EP) Reference Standard

PHR2640

Penicillin G potassium salt, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2644

Penicilline V potassium salt, Pharmaceutical Secondary Standard; Certified Reference Material

Y0002265

Procaine benzylpenicillin for peak identification A, European Pharmacopoeia (EP) Reference Standard

Y0002171

Procaine benzylpenicillin impurity F, European Pharmacopoeia (EP) Reference Standard

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H317

Classification des risques

Skin Sens. 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

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Certificats d'analyse (COA)

Lot/Batch Number

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Paul P Drury et al.
Neuropharmacology, 83, 62-70 (2014-04-15)
Basal ganglia injury after hypoxia-ischemia remains common in preterm infants, and is closely associated with later cerebral palsy. In the present study we tested the hypothesis that a highly selective neuronal nitric oxide synthase (nNOS) inhibitor, JI-10, would improve survival
Xiao-Jian Han et al.
International journal of molecular medicine, 35(4), 885-892 (2015-01-28)
Percutaneous coronary intervention [PCI or percutaneous transluminal coronary angioplasty (PTCA)] has been developed into a mature interventional treatment for atherosclerotic cardiovascular disease. However, the long-term therapeutic effect is compromised by the high incidence of vascular restenosis following angioplasty, and the
Matthieu Picard et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 113(1), 75-81 (2014-05-27)
The absence of commercially available penicilloyl-polylysine (PPL) for most of the last decade severely hampered the practice of penicillin allergy evaluation because skin testing without PPL is reported to have a poor negative predictive value (NPV). To determine the safety
Chronic inflammatory demyelinating polyneuropathy associated with neurosyphilis.
Evangelia Kararizou et al.
The American journal of the medical sciences, 349(1), 90-91 (2014-12-04)
Paul P Drury et al.
PloS one, 9(5), e96530-e96530 (2014-05-07)
The majority of pre-clinical studies of hypoxic-ischemic encephalopathy at term-equivalent have focused on either relatively mild insults, or on functional paradigms of cerebral ischemia or hypoxia-ischemia/hypotension. There is surprisingly little information on the responses to single, severe 'physiological' insults. In
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