122912
2-Amino-6,8-dihydroxypurine
Synonyme(s) :
2-Amino-6,8-purinediol, 8-Hydroxyguanine
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About This Item
Formule empirique (notation de Hill):
C5H5N5O2
Numéro CAS:
Poids moléculaire :
167.13
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352200
ID de substance PubChem :
Produits recommandés
Impuretés
<10% acetic acid
Chaîne SMILES
Nc1nc(O)c2[nH]c(O)nc2n1
InChI
1S/C5H5N5O2/c6-4-8-2-1(3(11)10-4)7-5(12)9-2/h(H5,6,7,8,9,10,11,12)
Clé InChI
CLGFIVUFZRGQRP-UHFFFAOYSA-N
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organes cibles
Respiratory system
Code de la classe de stockage
13 - Non Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
235.4 °F - closed cup
Point d'éclair (°C)
113 °C - closed cup
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Ilinca Nicolae et al.
Experimental and therapeutic medicine, 17(2), 1012-1019 (2019-01-27)
Recent data suggest that severe psoriasis is an independent risk factor for chronic renal disease. In the present study, we investigated the role of related-purine derivatives as predictors of renal dysfunctions in patients with psoriasis. A prospective study was conducted
Jia Guo et al.
Nucleic acids research, 41(16), 7700-7712 (2013-06-19)
Oxidized bases in DNA have been implicated in cancer, aging and neurodegenerative disease. We have developed an approach combining single-cell gel electrophoresis (comet) with fluorescence in situ hybridization (FISH) that enables the comparative quantification of low, physiologically relevant levels of
Ana-Maria Chiorcea-Paquim et al.
Mikrochimica acta, 188(2), 58-58 (2021-01-29)
Oxidative DNA damage plays an important role in the pathogenesis of various diseases. Among oxidative DNA lesions, 8-oxoguanine (8-oxoG) and its corresponding nucleotide 8-oxo-2'-deoxyguanosine (8-oxodG), the guanine and deoxyguanosine oxidation products, have gained much attention, being considered biomarkers for oxidative
Sara Timpano et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(4), 5716-5728 (2019-01-17)
Multicellular organisms balance oxygen delivery and toxicity by having oxygen pass through several barriers before cellular delivery. In human cell culture, these physiologic barriers are removed, exposing cells to higher oxygen levels. Human cells cultured in ambient air may appear
Eleonora Parlanti et al.
Free radical biology & medicine, 53(11), 2171-2177 (2012-09-27)
Although oxidatively damaged DNA is repaired primarily via the base excision repair (BER) pathway, it is now evident that multiple subpathways are needed. Yet, their relative contributions and coordination are still unclear. Here, mouse embryo fibroblasts (MEFs) from selected nucleotide
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