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GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Synonymes:
EPND, GluN2A, NMDAR2A, NR2A
Espèce(s):
Human GRIN2A (2903), Mouse Grin2a (14811), Rat Grin2a (24409), sheep GRIN2A (101106989), domestic guinea pig Grin2a (100727265), dog GRIN2A (490012), chicken GRIN2A (427678), domestic cat GRIN2A (101086110)
ID UniProtKB:
Q12879, O00669, Q17RZ6
ID du gène:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

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Small Molecule - Agonist

Numéro du produit
Description
Espèce(s)
239488
1,4-Bis(3-aminopropyl)piperazine, ≥95%,
Espèce(s)
rat
PHR1018
Dextromethorphan HBr, certified reference material, pharmaceutical secondary standard,
Espèce(s)
human
D-013
Dextromethorphan solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
1181007
Dextromethorphan hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
D9684
Dextromethorphan hydrobromide, meets USP testing specifications,
Espèce(s)
human

Small Molecule - Allosteric Modulator

Numéro du produit
Description
Espèce(s)
561479
4-Aminopiperidine, ,
Espèce(s)
rat
K-002
Ketamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
K0250
Kainic acid monohydrate, ≥99% (TLC),
Espèce(s)
human, mouse, rat
A6981
Acamprosate calcium, ≥98% (HPLC), powder,
Espèce(s)
human
1000554
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Espèce(s)
human

Small Molecule - Antagonist

Numéro du produit
Description
Espèce(s)
G7126
Glycine, ReagentPlus®, ≥99% (HPLC),
Espèce(s)
rat
G8898
Glycine, suitable for electrophoresis, ≥99%,
Espèce(s)
rat
50046
Glycine, BioUltra, Molecular Biology, ≥99.0% (NT),
Espèce(s)
rat
G8790
Glycine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%,
Espèce(s)
rat
G5417
Glycine, ,
Espèce(s)
rat

Antibodies

Numéro du produit
Description
Espèces réactives
Application
07-632
Anti-NR2A Antibody, Upstate®, from rabbit,
Espèces réactives
mouse, rat
Application
immunoprecipitation (IP)
western blot
AB1555P
Anti-NMDAR2A Antibody, Chemicon®, from rabbit,
Espèces réactives
fish, human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB5200888
Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse, clone S327-95, purified immunoglobulin,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
AB1548
Anti-NMDAR2A&B Antibody, pan, Chemicon®, from rabbit,
Espèces réactives
avian, guinea pig, human, mouse, rabbit, rat
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB5200978
Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse, clone S327A-38, purified immunoglobulin,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot

Small Molecule - Blocker

Numéro du produit
Description
Espèce(s)
D8816
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Espèce(s)
human
A7127
Agmatine sulfate salt, ≥97%, powder,
Espèce(s)
human
75517
Orphenadrine hydrochloride, ≥98.0% (AT),
Espèce(s)
human
Y0001181
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Y0000100
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
I5109
Indole-2-carboxylic acid, 98%,
Espèce(s)
rat, human
D207756
1,3-Diphenylguanidine, 97%,
Espèce(s)
rat, mouse, human
Q2128
Quisqualic acid, powder,
Espèce(s)
rat
N5501
Nω-Nitro-L-arginine, ≥98% (TLC),
Espèce(s)
rat, mouse, human
P0547
Pentamidine isethionate salt, powder,
Espèce(s)
human

Small Molecule - Mixed Agonist/Antagonist

Numéro du produit
Description
Espèce(s)
D23602
1,3-Diaminopropane, ≥99%,
Espèce(s)
rat
308110
N,N′-Dimethyl-1,3-propanediamine, 97%,
Espèce(s)
rat
D18609
1,3-Diamino-2-propanol, 95%,
Espèce(s)
rat
549983
N,N,N′,N′-Tetramethyl-1,3-propanediamine, ≥99%,
Espèce(s)
rat
226920
2,2-Dimethyl-1,3-propanediamine, 99%,
Espèce(s)
rat

esiRNA

Numéro du produit
Description
Espèce(s)
EHU040271
MISSION® esiRNA, targeting human GRIN2A,
Espèce(s)
human
EMU051581
MISSION® esiRNA, targeting mouse Grin2a,
Espèce(s)
mouse