1430735

Methylnaltrexone bromide

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): 17-(Cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-17-methyl-6-oxomorphinanium bromide, MNTX, Methylnaltrexonium, Mrz-2663, N-Methylnaltrexone, Naltrexone MB, Quaternary ammonium naltrexone
• Fórmula empírica (Notação de Hill): C₂₁H₂₆NO₄ · Br
• Número CAS: 73232-52-7
• Peso molecular: 436.34
• Número MDL: MFCD06407831
• Código UNSPSC: 41116107
• ID de substância PubChem: 329750446
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: methylnaltrexone
• fabricante/nome comercial: USP
• aplicação(ões): pharmaceutical
• formato: neat
• cadeia de caracteres SMILES: [Br-].C[N@+]1(CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@]2(O)CCC4=O)c35)CC6CC6
• InChI: 1S/C21H25NO4.BrH/c1-22(11-12-2-3-12)9-8-20-17-13-4-5-14(23)18(17)26-19(20)15(24)6-7-21(20,25)16(22)10-13;/h4-5,12,16,19,25H,2-3,6-11H2,1H3;1H/t16-,19+,20+,21-,22?;/m1./s1
• chave InChI: IFGIYSGOEZJNBE-KNLJMPJLSA-N
• Informações sobre genes: human ... OPRM1(4988)

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Methylnaltrexone bromide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Ações bioquímicas/fisiológicas

Methylnaltrexone bromide is a narcotic antagonist. It is a peripheral mu-opiod receptor antagonist that cannot cross the blood-brain barrier. It reverses many opioid side-effects without interfering with pain relief.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS08
• Palavra indicadora: Warning
• Frases de perigo: H371
• Declarações de precaução: P260 - P264 - P270 - P308 + P311 - P405 - P501
• Classificações de perigo: STOT SE 2 Oral
• Órgãos-alvo: Gastrointestinal tract
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable