1338313

Imiquimod

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): Imiquimod, 1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine
• Fórmula empírica (Notação de Hill): C₁₄H₁₆N₄
• Número CAS: 99011-02-6
• Peso molecular: 240.30
• Número MDL: MFCD00866946
• Código UNSPSC: 41116107
• ID de substância PubChem: 329750158
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: imiquimod
• fabricante/nome comercial: USP
• aplicação(ões): pharmaceutical (small molecule)
• formato: neat
• cadeia de caracteres SMILES: CC(C)Cn1cnc2c(N)nc3ccccc3c12
• InChI: 1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)
• chave InChI: DOUYETYNHWVLEO-UHFFFAOYSA-N
• Informações sobre genes: human ... TLR7(51284)

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Imiquimod USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Imiquimod Cream

Ações bioquímicas/fisiológicas

Imiquimod is a caspase 3 activator, which directly induces procaspase 3 cleavage to active caspase 3. Imiquimod induces apoptosis in vivo in basal cell carcinoma. Its anti-tumor activity is related to the induction of apoptosis. Imiquimod has anti-angiogenic, anti-inflammatory, anti-viral activities. Imiquimod also acts as an immune response modulator inducing the secretion of various cytokines and chemokines.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS06
• Palavra indicadora: Danger
• Frases de perigo: H301,H315,H319
• Declarações de precaução: P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Classificações de perigo: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable