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1043706

USP

Éster metílico de Asp-Phe

United States Pharmacopeia (USP) Reference Standard

Sinônimo(s):

éster metílico de N-(L-αaspartil)-L-fenilalanina, Asp-Phe-OMe, Aspartame

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About This Item

Fórmula linear:
HOOCCH2CH(NH2)CONHCH(CH2C6H5)COOCH3
Número CAS:
22839-47-0
Peso molecular:
294.30
Beilstein:
2223850
Número MDL:
MFCD00002724
Código UNSPSC:
41116107
ID de substância PubChem:
329749070
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

aspartame

fabricante/nome comercial

USP

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

cadeia de caracteres SMILES

COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(O)=O

InChI

1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1

chave InChI

IAOZJIPTCAWIRG-QWRGUYRKSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Aspartame USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Asp-Phe 96%

Sigma-Aldrich

421669

Asp-Phe

Sodium Cyclamate analytical standard

Supelco

47827

Sodium Cyclamate

Sucralose ≥98.0% (HPLC)

Sigma-Aldrich

69293

Sucralose

Sacarina ≥99%

Sigma-Aldrich

240931

Sacarina

B A Magnuson et al.
Critical reviews in toxicology, 37(8), 629-727 (2007-09-11)
Aspartame is a methyl ester of a dipeptide used as a synthetic nonnutritive sweetener in over 90 countries worldwide in over 6000 products. The purpose of this investigation was to review the scientific literature on the absorption and metabolism, the
Karol Rycerz et al.
Folia neuropathologica, 51(1), 10-17 (2013-04-05)
Aspartame, a widespread sweetener used in many food products, is considered as a highly hazardous compound. Aspartame was discovered in 1965 and raises a lot of controversy up to date. Astrocytes are glial cells, the presence and functions of which
Harriett H Butchko et al.
Regulatory toxicology and pharmacology : RTP, 35(2 Pt 2), S1-93 (2002-08-16)
Over 20 years have elapsed since aspartame was approved by regulatory agencies as a sweetener and flavor enhancer. The safety of aspartame and its metabolic constituents was established through extensive toxicology studies in laboratory animals, using much greater doses than
S E Shephard et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 31(5), 323-329 (1993-05-01)
Naturally occurring dipeptides, cholecystokinine (CCK, a tetrapeptide hormone) and the artificial sweetener aspartame were nitrosated for 10-30 min with 40 mM-nitrite (pH 3.5, 37 degrees C), and the resultant products examined for mutagenicity in Salmonella typhimurium TA100. Specific mutagenicities (net
P Humphries et al.
European journal of clinical nutrition, 62(4), 451-462 (2007-08-09)
The use of the artificial sweetener, aspartame, has long been contemplated and studied by various researchers, and people are concerned about its negative effects. Aspartame is composed of phenylalanine (50%), aspartic acid (40%) and methanol (10%). Phenylalanine plays an important
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