47864

Nicotinic acid

analytical standard

• Sinônimo(s): 3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B₃
• Fórmula empírica (Notação de Hill): C₆H₅NO₂
• Número CAS: 59-67-6
• Peso molecular: 123.11
• Beilstein: 109591
• Número CE: 200-441-0
• Número MDL: MFCD00006391
• Código UNSPSC: 12164500
• ID de substância PubChem: 24871534

Propriedades

• grau: analytical standard
• Certificado de análise (CofA): current certificate can be downloaded
• Características: standard type water soluble vitamin
• embalagem: ampule of 1000 mg
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• pf: 236-239 °C (lit.)
• densidade: 1.473 g/cm³ at 25 °C
• aplicação(ões): pharmaceutical (small molecule); vitamins, nutraceuticals, and natural products
• formato: neat
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: OC(=O)c1cccnc1
• InChI: 1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
• chave InChI: PVNIIMVLHYAWGP-UHFFFAOYSA-N
• Informações sobre genes: human ... CYP1A2(1544) ; rat ... Chrnb2(54239)

Descrição

Descrição geral

Nicotinic acid acts as an antilipolytic drug in adipose tissue, and is commonly used for hyperlipoproteinaemia and pellagra.

Nicotinic acid is a water soluble, vitamin belonging to B complex group of vitamins, which can be used as a broad spectrum lipid lowering drug. Its mode of action basically involves the inhibition of the hormone-sensitive triglyceride lipase and thereby, decreasing the lipolysis in adipose tissue.

Aplicação

Nicotinic acid may be used as an analytical reference standard for the quantification of the analyte in tablet dosage forms using reversed-phase high-performance liquid chromatography technique.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H319
• Declarações de precaução: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Classificações de perigo: Eye Irrit. 2
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 379.4 °F - closed cup
• Ponto de fulgor (°C): 193 °C - closed cup
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves