U3750

Uridine

≥99%

• Sinônimo(s): 1-β-D-Ribofuranosyluracil, Uracil-1-β-D-ribofuranoside
• Fórmula empírica (Notação de Hill): C₉H₁₂N₂O₆
• Número CAS: 58-96-8
• Peso molecular: 244.20
• Beilstein: 754902
• Número CE: 200-407-5
• Número MDL: MFCD00006526
• Código UNSPSC: 41106305
• ID de substância PubChem: 24900640
• NACRES: NA.51

Propriedades

• fonte biológica: synthetic (organic)
• Nível de qualidade: 200
• Ensaio: ≥99%
• forma: powder
• pf: 163-167 °C (lit.)
• solubilidade: H₂O: 50 mg/mL, clear, colorless
• cadeia de caracteres SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
• chave InChI: DRTQHJPVMGBUCF-XVFCMESISA-N
• Informações sobre genes: mouse ... Uck1(22245)

Descrição

Descrição geral

Uridine is a uracil nucleoside, specific for RNA sequence. Uridine is present in blood, seminal fluid and cerebrospinal fluid. Uridine is synthesized in living organisms by de novo and salvage pathways.

Aplicação

Uridine has been used:

• as a component of hippocampal neuron medium for culture of primary hippocampal neuron cells
• in uridine rescue experiments in mouse embryonic fibroblasts and human breast cancer cells
• in chase sequencing experiments

Ações bioquímicas/fisiológicas

Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine are implicated in insulin resistance.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)