T6319

Anti-TOM22 antibody , Mouse monoclonal

clone 1C9-2, purified from hybridoma cell culture

• Sinônimo(s): Anti-Mitochondrial import receptor Tom22, Anti-TOMM22, Anti-Translocase of outer mitochondrial membrane 22 homolog (yeast)
• Número MDL: MFCD03457578
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• conjugado: unconjugated
• forma do anticorpo: purified from hybridoma cell culture
• tipo de produto de anticorpo: primary antibodies
• clone: 1C9-2, monoclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 22 kDa
• reatividade de espécies: human, monkey
• não deve reagir com: rodent
• concentração: ~1 mg/mL
• técnica(s): immunocytochemistry: suitable; microarray: suitable; western blot: 0.5-1.0 μg/mL using whole extract of cultured human lymphoma Raji cells.
• Isotipo: IgG1
• nº de adesão UniProt: Q9NS69
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... TOMM22(56993)

Descrição

Descrição geral

Translocase of outer mitochondrial membrane 22 (TOMM22) is an essential receptor of the mitochondrial import channel. It is characterized with an N-terminal negatively charged region exposed to the cytosol, a putative transmembrane region and a C-terminal intermembrane space region with little negative charge.

Imunogênio

membrane fraction from Vero (monkey kidney-derived) cells.

Aplicação

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

• Western blotting

Ações bioquímicas/fisiológicas

Translocase of outer mitochondrial membrane 22 (TOMM22) is a key constituent of TOM complex. It functions as a mitochondrial receptor for the proapoptotic protein Bax (BCL2-associated X protein). TOMM22 interacts with 3-β hydroxysteroid dehydrogenase 2 (3βHSD2) and converts pregnenolone-to-progesterone in steroidogenic cells.

forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable