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T3165

Sigma-Aldrich

7-Methoxy-4-(trifluoromethyl)coumarin

≥99% (TLC)

Sinônimo(s):

Methyl 4-(trifluoromethyl)umbelliferyl ether

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About This Item

Fórmula empírica (Notação de Hill):
C11H7F3O3
Número CAS:
575-04-2
Peso molecular:
244.17
Beilstein:
225039
Número MDL:
MFCD00132980
Código UNSPSC:
12352204
ID de substância PubChem:
24900113
NACRES:
NA.32

Ensaio

≥99% (TLC)

forma

powder

solubilidade

acetone: 50 mg/mL, clear, colorless to faintly yellow

fluorescência

λex 333 nm; λem 416 nm in methanol

cadeia de caracteres SMILES

COc1ccc2c(OC(=O)C=C2C(F)(F)F)c1

InChI

1S/C11H7F3O3/c1-16-6-2-3-7-8(11(12,13)14)5-10(15)17-9(7)4-6/h2-5H,1H3

chave InChI

HAZHUELNIGDYQH-UHFFFAOYSA-N

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Categorias relacionadas

Aplicação

7-Methoxy-4-(trifluoromethyl)coumarin has been used as a substrate in cytochrome P450 2E1 (CYP2E1) activity assay and aromatase assay.

Ações bioquímicas/fisiológicas

The enzymatic action of cytochrome P450 2E1 (CYP2E1) on 7-methoxy-4-(trifluoromethyl)coumarin results in a fluorescent product 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) that can be measured at 409/530 nm.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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