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T1875

Sigma-Aldrich

Testosterone propionate

solid

Sinônimo(s):

17β-Hydroxy-4-androsten-3-one 17-propionate, 17β-Propionyloxy-4-androsten-3-one, 4-Androsten-17β-ol-3-one 17-propionate

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About This Item

Fórmula empírica (Notação de Hill):
C22H32O3
Número CAS:
57-85-2
Peso molecular:
344.49
Beilstein:
3221760
Número CE:
200-351-1
Número MDL:
MFCD00003653
Código UNSPSC:
51111800
ID de substância PubChem:
24899994
NACRES:
NA.77

fonte biológica

synthetic (organic)

Nível de qualidade

200

esterilidade

non-sterile

Ensaio

≥98% (HPLC)

forma

solid

controle de medicamentos

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

cor

white

solubilidade

acetone: soluble 1 in 4 of acetone
chloroform: soluble 50 mg/ml, clear, colorless to faintly yellow
ethanol: soluble 1 in 6 of ethanol
ethyl oleate: soluble 1 in 20 of ethyl oleate
propylene glycol: soluble 1 in 30 of propylene glycol
soluble 1 in 20 of ethyl oleate
ethanol: 10 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.4 mg/mL
H2O: insoluble
oil: soluble

Condições de expedição

ambient

temperatura de armazenamento

room temp

cadeia de caracteres SMILES

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])OC(=O)CC

InChI

1S/C22H32O3/c1-4-20(24)25-19-8-7-17-16-6-5-14-13-15(23)9-11-21(14,2)18(16)10-12-22(17,19)3/h13,16-19H,4-12H2,1-3H3/t16-,17-,18-,19-,21-,22-/m0/s1

chave InChI

PDMMFKSKQVNJMI-BLQWBTBKSA-N

Informações sobre genes

human ... AR(367) , CYP17A1(1586)
rat ... Ar(24208)

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Aplicação

Testosterone propionate has been used for studying its effects on pregnant ewes,.

Ações bioquímicas/fisiológicas

Androgens direct the development of the male phenotype during embryogenesis and at puberty. Testosterone is an androgen that is secreted by the testis. This hormone is converted to dihydrotestosterone in the target tissues where it regulates several biological functions. Testosterone propionate has been synthetically derived from a plant. This product has extended and faster-acting functions when compared to other testosterone esters.

forma física

Photosensitive solid

Nota de preparo

This product is soluble in chloroform (50 mg/ml). It is also soluble in various oils. The oil solutions can be sterilized by maintaining at 150 deg C for 1 hour. It is practically insoluble in water, soluble 1 in 6 of ethanol, 1 in 4 of acetone, 1 in 20 of ethyl oleate, and 1 in 30 of propylene glycol. The product is incompatible with alkalis and oxidizing agents and it should be protected from light.

Palavra indicadora

Danger

Frases de perigo

H302,H351,H360FD,H400

Classificações de perigo

Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Repr. 1A

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Equipamento de proteção individual

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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M E Rose et al.
Infection and immunity, 26(2), 630-637 (1979-11-01)
Comparisons were made between infections with Eimeria spp. in normal animals and in animals with functional deficiencies in either T-lymphocytes (athymic nude rats) or B-lymphocytes (bursectomized chickens). Approximately three times more oocysts of E. nieschulzi were passed during a primary
Maria Cernea et al.
Endocrinology, 156(9), 3277-3291 (2015-06-11)
Prenatal testosterone (T)-treated ewes display a constellation of reproductive defects that closely mirror those seen in PCOS women, including altered hormonal feedback control of GnRH. Kisspeptin/neurokinin B/dynorphin (KNDy) neurons of the arcuate nucleus (ARC) play a key role in steroid
Tsuyoshi Shimmura et al.
Scientific reports, 9(1), 3978-3978 (2019-03-10)
Animals that communicate using sound are found throughout the animal kingdom. Interestingly, in contrast to human vocal learning, most animals can produce species-specific patterns of vocalization without learning them from their parents. This phenomenon is called innate vocalization. The underlying
James J Li et al.
Journal of medicinal chemistry, 50(13), 3015-3025 (2007-06-08)
A novel series of imidazolin-2-ones were designed and synthesized as highly potent, orally active and muscle selective androgen receptor modulators (SARMs), with most of the compounds exhibiting low nM in vitro potency in androgen receptor (AR) binding and functional assays.
Carlo Serra et al.
The journals of gerontology. Series A, Biological sciences and medical sciences, 68(1), 17-26 (2012-04-14)
Aging is associated with loss of muscle mass and strength, reduced satellite cell number, and lower regenerative potential. Testosterone increases muscle mass, strength, and satellite cell number in humans; however, the effects of testosterone on the regenerative potential of skeletal
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