SRP3279

BMP-5 human

recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC)

• Sinônimo(s): none
• Código UNSPSC: 12352202
• NACRES: NA.32

Propriedades

• fonte biológica: human
• recombinante: expressed in CHO cells
• Ensaio: ≥95% (HPLC); ≥95% (SDS-PAGE)
• forma: lyophilized
• potência: 0.5-1.0 μg/mL ED₅₀
• peso molecular: 31.2 kDa
• embalagem: pkg of 10 μg
• Impurezas: <0.1 EU/μg endotoxin, tested
• cor: white to off-white
• nº de adesão UniProt: P22003
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• Informações sobre genes: human ... BMP5(653)

Descrição

Descrição geral

As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs.

Ações bioquímicas/fisiológicas

TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. BMP-5 is expressed in the nervous system, lung and liver. It is a known regulator for dendritic growth in sympathetic neurons. BMP-5 is a 454 amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein. Recombinant human BMP-5 is a 15.6 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains.

forma física

Lyophilized with no additives.

Reconstituição

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable