SML3947

PSB12379

≥98% (HPLC)

• Sinônimo(s): Placeholder name, N-(Phenylmethyl)-adenosine-5′-[hydrogen P-(phosphonomethyl)phosphonate] sodium salt, N6-Benzylpurine riboside-5′-O-[(phosphonomethyl)-phosphonic acid sodium salt
• Fórmula empírica (Notação de Hill): C₁₈H₂₃N₅O₉P₂. xNa
• Código UNSPSC: 12352200
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥98% (HPLC)
• Formulário: powder
• condição de armazenamento: desiccated
• cor: white to beige
• solubilidade: H₂O: 2 mg/mL, clear
• temperatura de armazenamento: 2-8°C

Descrição

Ações bioquímicas/fisiológicas

Potent and selective ecto-5′-nucleotidase (CD73, eN) Inhibitor.

PSB12379 is a potent and selective ecto-5′-nucleotidase (CD73, eN) Inhibitor (recombinant human/rat eN Ki = 2.21/9.03 nM; human serum eN Ki = 18.8 nM; Ki >>10 μM against NTPDase 1/2/3 & NPP 1/2/3). Umbilical cord mesenchymal stem cell-derived small extracellular vesicles (UCMSC-sEV) is reported to promote the proliferation and migration of pediatric urethral smooth muscle cells (PUSMCs) in cultures by CD73-catalyzed production of adenosine, which can be blocked by PSB12379.

Atenção

Hygroscopic

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable