Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos

SML3286

Sigma-Aldrich

cUMP sodium salt

≥98% (HPLC)

Sinônimo(s):

3’,5’-cyclic uridine monophosphate sodium salt, CID 3081385 sodium, Uridine cyclic 3′,5′-monophosphate monosodium salt, cyclic UMP sodium

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Fórmula empírica (Notação de Hill):
C9H10N2O8P·Na
Número CAS:
56632-58-7
Peso molecular:
328.15
Número MDL:
MFCD00134914
Código UNSPSC:
12352200
NACRES:
NA.32

Nível de qualidade

100

Ensaio

≥98% (HPLC)

forma

powder

cor

white to beige

solubilidade

DMSO: 2 mg/mL, clear

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

O[C@H]1[C@@](N2C(NC(C=C2)=O)=O)([H])O[C@@]3([H])[C@@]1([H])OP(OC3)(O[Na])=O

InChI

1S/C9H11N2O8P.Na/c12-5-1-2-11(9(14)10-5)8-6(13)7-4(18-8)3-17-20(15,16)19-7;/h1-2,4,6-8,13H,3H2,(H,15,16)(H,10,12,14);/q;+1/p-1

chave InChI

APYWIKXPIFYSBG-UHFFFAOYSA-M

Descrição geral

3’,5’-cyclic uridine monophosphate (cUMP) is a cyclic pyrimidine nucleotide. cUMP (3’,5’-cyclic uridine monophosphate) sodium salt is a secondary messenger functioning in bacterial immunity against viruses.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Jieqiong Zhang et al.
Cell reports, 27(9), 2679-2689 (2019-05-30)
Cellular inhibitor of apoptosis proteins cIAP1 and cIAP2 ubiquitinate nuclear factor κB (NF-κB)-inducing kinase (NIK) to suppress non-canonical NF-κB signaling and substrates such as receptor interacting protein kinase 1 (RIPK1) to promote cell survival. We investigate how these functions contribute to
Sander de Kivit et al.
Nature metabolism, 2(10), 1046-1061 (2020-09-23)
Following activation, conventional T (Tconv) cells undergo an mTOR-driven glycolytic switch. Regulatory T (Treg) cells reportedly repress the mTOR pathway and avoid glycolysis. However, here we demonstrate that human thymus-derived Treg (tTreg) cells can become glycolytic in response to tumour
Nicole Blaquiere et al.
Journal of medicinal chemistry, 61(15), 6801-6813 (2018-06-26)
NF-κB-inducing kinase (NIK) is a protein kinase central to the noncanonical NF-κB pathway downstream from multiple TNF receptor family members, including BAFF, which has been associated with B cell survival and maturation, dendritic cell activation, secondary lymphoid organ development, and
Weisong Duan et al.
Molecular neurobiology, 58(5), 2435-2446 (2021-01-14)
TANK-binding kinase1 (TBK1) haploinsufficiency has been shown to cause both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD); however, the mechanism is unclear. Myeloid Tbk1 knockout mice (Tbk1-LKO mice) were established and motor function and pathological analyses were also performed.
Jiang Wang et al.
Pathogens and disease, 78(7) (2020-08-30)
Periodontitis is an inflammatory disease that causes damages to periodontium and alveolar bone. Overactivation and formation of osteoclasts can cause bone destruction, which contributes to periodontitis development. Receptor activator of nuclear factor κB ligand (RANKL)-mediated NF-κB signaling plays an essential
Exibir todos os documentos relacionados

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica