SML2004

Cangrelor tetrasodium salt

≥95% (HPLC)

• Sinônimo(s): AR-C69931 tetrasodium salt, AR-C69931MX tetrasodium salt, N-[2-(methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]-, anhydride with P,P′-(dichloromethylene)bis[phosphonic acid]-5′-Adenylic acid tetrasodium salt
• Fórmula empírica (Notação de Hill): C₁₇H₂₁Cl₂F₃N₅O₁₂P₃S₂·Na₄
• Número CAS: 163706-36-3
• Peso molecular: 864.29
• Código UNSPSC: 12352200
• NACRES: NA.77

Propriedades

• Ensaio: ≥95% (HPLC)
• Formulário: powder
• cor: white to beige
• solubilidade: H₂O: 2 mg/mL, clear
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O[C@@H]1[C@H](O)[C@@H](COP(OP(C(Cl)(Cl)P(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O)O[C@H]1N(C=N2)C3=C2C(NCCSC)=NC(SCCC(F)(F)F)=N3
• InChI: 1S/C17H25Cl2F3N5O12P3S2.4Na/c1-43-5-3-23-12-9-13(26-15(25-12)44-4-2-16(20,21)22)27(7-24-9)14-11(29)10(28)8(38-14)6-37-42(35,36)39-41(33,34)17(18,19)40(30,31)32;;;;/h7-8,10-11,14,28-29H,2-6H2,1H3,(H,33,34)(H,35,36)(H,23,25,26)(H2,30,31,32);;;;/q;4*+1/p-4/t8-,10-,11-,14-;;;;/m1..../s1
• chave InChI: COWWROCHWNGJHQ-OPKBHZIBSA-J

Descrição

Aplicação

Cangrelor has been used as a purinergic receptor P2Y12 antagonist to study its effects on neuromedin U receptor 2 (NMUR2)-coupled Gαi pathway during platelet aggregation.[1]

Ações bioquímicas/fisiológicas

Cangrelor is a potent and selective platelet P2Y12 antagonist. It is used as an intravenous antiplatelet drug to prevent formation of harmful blood clots in the coronary arteries.

Cangrelor is an analog of nonthienopyridine adenosine triphosphate. It has a therapeutic effect against reversible platelet inhibition.[2]

Potent and selective platelet P2Y12 antagonist

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable