SML1176

Carboxypyridostatin trifluoroacetate salt

≥95% (HPLC)

• Sinônimo(s): 4-[[[2,6-Bis[[[4-(2-aminoethoxy)-2-quinolinyl]amino]carbonyl]-4-pyridinyl]oxy]methyl]-1H-1,2,3-triazole-1-propanoic acid trifluoroacetate salt, carboxyPDS trifluoroacetate salt
• Fórmula empírica (Notação de Hill): C₃₅H₃₄N₁₀O₇ · xC₂HF₃O₂
• Número CAS: 1417638-60-8
• Peso molecular: 706.71 (free base basis)
• Código UNSPSC: 12352200
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥95% (HPLC)
• Formulário: powder
• condição de armazenamento: desiccated
• cor: white to light brown
• solubilidade: H₂O: 25 mg/mL, clear
• temperatura de armazenamento: −20°C

Descrição

Aplicação

Carboxypyridostatin trifluoroacetate salt has been used in the study of translation, stimulated by DHX36 (DEAH-box helicase 36) binding at G-rich sites in mRNA untranslated regions.

Ações bioquímicas/fisiológicas

Carboxypyridostatin (carboxyPDS) selectively stabilizes RNA-containg G-quadruplex stuctures.

Carboxypyridostatin (carboxyPDS) selectively stabilizes RNA-containg G-quadruplex stuctures. Immunofluorescent staining of carboxyPDS treated cells using an anti G-quadruplex antibody reveals staining only in the cytoplasm and not the nucleus, demonstrating selectivity against DNA G-quadruplex structures.

Outras notas

Light sensitive

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable