SML0121

BTZO-1

≥98% (HPLC)

• Sinônimo(s): 2-Pyridin-2-yl-4H-1,3-benzothiazin-4-one
• Fórmula empírica (Notação de Hill): C₁₃H₈N₂OS
• Número CAS: 99420-15-2
• Peso molecular: 240.28
• Número MDL: MFCD19690951
• Código UNSPSC: 12352200
• ID de substância PubChem: 329825172
• NACRES: NA.77

Propriedades

• Ensaio: ≥98% (HPLC)
• Formulário: powder
• cor: white to tan
• solubilidade: DMSO: ≥7 mg/mL
• originador: Takeda
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O=C1N=C(Sc2ccccc12)c3ccccn3
• InChI: 1S/C13H8N2OS/c16-12-9-5-1-2-7-11(9)17-13(15-12)10-6-3-4-8-14-10/h1-8H
• chave InChI: GBAKVEWPYUIGHN-UHFFFAOYSA-N

Descrição

Aplicação

BTZO-1 may be used in ARE-mediated gene expression studies.

Ações bioquímicas/fisiológicas

BTZO-1 is a suppressor of cardiomyocyte apoptosis presumably by activation of antioxidant response element (ARE)-mediated gene expression. BTZO-1 binds to the macrophage migration inhibitory factor (MIF) that is required to activate the glutathione S-transferase Ya subunit (GST Ya) gene ARE.

suppressor of cardiomyocyte apoptosis; ligand of macrophage migration inhibitory factor (MIF)

Características e benefícios

This compound was developed by Takeda. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable